Chromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 85 million base pairs (the building material of DNA) and represents about 2.5 percent of the total DNA in cells.Tetrasomy 18p results from the presence of an abnormal extra chromosome, called an isochromosome 18p, in each cell. An isochromosome is a chromosome with two identical arms. Normal chromosomes have one long (q) arm and one short (p) arm, but isochromosomes have either two q arms or two p arms. Isochromosome 18p is a version of chromosome 18 made up of two p arms.Cells normally have two copies of each chromosome, one inherited from each parent. In people with tetrasomy 18p, cells have the usual two copies of chromosome 18 plus an isochromosome 18p.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Dynactin Associated Protein (DYNAP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Dynactin Associated Protein (DYNAP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Dynactin Associated Protein (DYNAP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Dynactin Associated Protein (DYNAP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dynactin Associated Protein (DYNAP) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Dynactin Associated Protein (DYNAP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Dynactin Associated Protein (DYNAP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Dynactin Associated Protein (DYNAP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Dynactin Associated Protein (DYNAP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dynactin Associated Protein (DYNAP) | ELISA Kit Customized Service Offer |
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- "DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]
- "A novel human dynactin-associated protein, dynAP, promotes activation of Akt, and ergosterol-related compounds induce dynAP-dependent apoptosis of human cancer cells."Mol. Cancer Ther. 9:2934-2942(2010) [PubMed] [Europe PMC] [Abstract]