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Chromosome 15 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 15 spans about 106 million base pairs (the building material of DNA) and represents between 3% and 3.5% of the total DNA in cells.
A type of blood cancer known as acute promyelocytic leukemia is caused by a rearrangement (translocation) of genetic material between chromosomes 15 and 17. This translocation, written as t(15;17), fuses part of the PML gene from chromosome 15 with part of the RARA gene from chromosome 17. This mutation is acquired during a person's lifetime and is present only in certain cells. This type of genetic change, called a somatic mutation, is not inherited.
A type of blood cancer known as acute promyelocytic leukemia is caused by a rearrangement (translocation) of genetic material between chromosomes 15 and 17. This translocation, written as t(15;17), fuses part of the PML gene from chromosome 15 with part of the RARA gene from chromosome 17. This mutation is acquired during a person's lifetime and is present only in certain cells. This type of genetic change, called a somatic mutation, is not inherited.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Chromosome 15 Open Reading Frame 41 (C15orf41) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Chromosome 15 Open Reading Frame 41 (C15orf41) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Chromosome 15 Open Reading Frame 41 (C15orf41) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Chromosome 15 Open Reading Frame 41 (C15orf41) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Chromosome 15 Open Reading Frame 41 (C15orf41) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Chromosome 15 Open Reading Frame 41 (C15orf41) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Chromosome 15 Open Reading Frame 41 (C15orf41) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Chromosome 15 Open Reading Frame 41 (C15orf41) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Chromosome 15 Open Reading Frame 41 (C15orf41) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Chromosome 15 Open Reading Frame 41 (C15orf41) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Chromosome 15 Open Reading Frame 41 (C15orf41) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Chromosome 15 Open Reading Frame 41 (C15orf41) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Chromosome 15 Open Reading Frame 41 (C15orf41) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Chromosome 15 Open Reading Frame 41 (C15orf41) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Chromosome 15 Open Reading Frame 41 (C15orf41) | ELISA Kit Customized Service Offer |
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- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I."Haematologica 98:1383-1387(2013) [PubMed] [Europe PMC] [Abstract]