TraB Domain Containing Protein 2A (TRABD2A)
[Edit]C2orf89; TIKI1; Chromosome 2 Open Reading Frame 89; Metalloprotease TIKI1
Chromosome 2 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 2 is the second largest human chromosome, spanning more than 237 million base pairs (the building material of DNA) and representing almost 8% of the total DNA in cells.
Changes in chromosome 2 have been identified in several types of cancer. These genetic changes are somatic, which means they are acquired during a person's lifetime and are present only in certain cells. For example, a rearrangement (translocation) of genetic material between chromosomes 2 and 3 has been associated with cancers of a certain type of blood cell originating in the bone marrow.Trisomy 2, in which cells have three copies of chromosome 2 instead of the usual two copies, has been found in myelodysplastic syndrome.
Changes in chromosome 2 have been identified in several types of cancer. These genetic changes are somatic, which means they are acquired during a person's lifetime and are present only in certain cells. For example, a rearrangement (translocation) of genetic material between chromosomes 2 and 3 has been associated with cancers of a certain type of blood cell originating in the bone marrow.Trisomy 2, in which cells have three copies of chromosome 2 instead of the usual two copies, has been found in myelodysplastic syndrome.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant TraB Domain Containing Protein 2A (TRABD2A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to TraB Domain Containing Protein 2A (TRABD2A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to TraB Domain Containing Protein 2A (TRABD2A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for TraB Domain Containing Protein 2A (TRABD2A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for TraB Domain Containing Protein 2A (TRABD2A) | ELISA Kit Customized Service Offer |
- "Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation."Cell 149:1565-1577(2012) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]