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Protein C10 (C10)

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GRCC10; C12orf57

Protein C10 (C10)
CCC W526
HGNC 29521
MGI 1315201
UniProt Q99622
The Human Genome Project has created a formidable challenge: the extraction of biological information from extensive amounts of raw sequence. With the increasing availability of genomic sequence from other species, one approach to extracting coding and regulatory element information is through cross-species sequence comparison. To assess the strengths and weaknesses of this methodology for large-scale sequence analysis, 227 kb of mouse sequence syntenic to a gene-rich cluster on human chromosome 12p13 was obtained. Primarily through percent identity plots (PIPs) of SIM comparative sequence alignments, the sequence of coding regions, putative alternative exons, conserved noncoding regions, and correlation in repetitive element insertions were easily determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein C10 (C10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein C10 (C10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein C10 (C10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein C10 (C10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein C10 (C10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein C10 (C10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein C10 (C10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein C10 (C10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein C10 (C10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein C10 (C10) ELISA Kit Customized Service Offer
  1. "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination."Genome Res. 7:268-280(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  7. "Whole-exome sequencing identifies mutated c12orf57 in recessive corpus callosum hypoplasia."Am. J. Hum. Genet. 92:392-400(2013) [PubMed] [Europe PMC] [Abstract]
  8. "A newly recognized autosomal recessive syndrome affecting neurologic function and vision."Am. J. Med. Genet. A 161:1207-1213(2013) [PubMed] [Europe PMC] [Abstract]
  9. "Mutations in c12orf57 cause a syndromic form of colobomatous microphthalmia."Am. J. Hum. Genet. 92:387-391(2013) [PubMed] [Europe PMC] [Abstract]