Chromosome 1 Open Reading Frame 95 (C1orf95)

C1orf95 Belongs to the SPEC3 family.Chromosome 1 is the largest of the human chromosomes, containing approximately 8% of all human genetic information. Rearrangements and mutations of chromosome 1 are prevalent in cancer and many other diseases. Patterns of sequence variation reveal signals of recent selection in specific genes that may contribute to human fitness, and also in regions where no function is evident. Fine-scale recombination occurs in hotspots of varying intensity along the sequence, and is enriched near genes. These and other studies of human biology and disease encoded within chromosome 1 are made possible with the highly accurate annotated sequence, as part of the completed set of chromosome sequences that comprise the reference human genome.