TSSK6 Activating Co-Chaperone Protein (TSACC)

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C1orf82; SSTK-IP; SSTK Interacting Protein; Chromosome 1 Open Reading Frame 82

TSSK6 Activating Co-Chaperone Protein (TSACC)
Mouse embryonic fibroblasts (MEFs) were transfected with retroviruses, resulting in random retroviral integration in their genomes and then co-inoculated with tumor cells into mice.Genomic analysis of co-inoculated stromal cells recovered from tumors showed clone-specific selection of cells with certain mutations during tumor progression.
Four integration sites were detected after in vivo selection, including Tubulin-tyrosine ligase (TTL), Histone 1, Rhesus blood group-associated B glycoprotein (RHGB) and SSTK-interacting protein (SSTK IP). TTL silencing promoted tumor growth. The retrovirus-mediated insertional mutagenesis may provide a valuable means for identifying genes involved in the interactions between tumor and stromal cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TSSK6 Activating Co-Chaperone Protein (TSACC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) CLIA Kit Customized Service Offer
n/a ELISA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TSSK6 Activating Co-Chaperone Protein (TSACC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) CLIA Kit Customized Service Offer
n/a ELISA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TSSK6 Activating Co-Chaperone Protein (TSACC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) CLIA Kit Customized Service Offer
n/a ELISA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) ELISA Kit Customized Service Offer
  1. "Identification of a novel HSP70-binding cochaperone critical to HSP90-mediated activation of small serine/threonine kinase."J. Biol. Chem. 285:35180-35187(2010) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]