TSSK6 Activating Co-Chaperone Protein (TSACC)
[Edit]C1orf82; SSTK-IP; SSTK Interacting Protein; Chromosome 1 Open Reading Frame 82
Mouse embryonic fibroblasts (MEFs) were transfected with retroviruses, resulting in random retroviral integration in their genomes and then co-inoculated with tumor cells into mice.Genomic analysis of co-inoculated stromal cells recovered from tumors showed clone-specific selection of cells with certain mutations during tumor progression.
Four integration sites were detected after in vivo selection, including Tubulin-tyrosine ligase (TTL), Histone 1, Rhesus blood group-associated B glycoprotein (RHGB) and SSTK-interacting protein (SSTK IP). TTL silencing promoted tumor growth. The retrovirus-mediated insertional mutagenesis may provide a valuable means for identifying genes involved in the interactions between tumor and stromal cells.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant TSSK6 Activating Co-Chaperone Protein (TSACC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant TSSK6 Activating Co-Chaperone Protein (TSACC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant TSSK6 Activating Co-Chaperone Protein (TSACC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to TSSK6 Activating Co-Chaperone Protein (TSACC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for TSSK6 Activating Co-Chaperone Protein (TSACC) | ELISA Kit Customized Service Offer |
- "Identification of a novel HSP70-binding cochaperone critical to HSP90-mediated activation of small serine/threonine kinase."J. Biol. Chem. 285:35180-35187(2010) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]