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Centriolar Coiled Coil Protein Of 110kDa (CCP110)

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CEP110; CP110; Centrosomal Protein Of 110 kDa

Centriolar Coiled Coil Protein Of 110kDa (CCP110)
CCC W793
HGNC 24342
MGI 2141942
PubMed 12361598
RGD 1310509
UniProt O43303
Wiki CCP110
Centrosome duplication and separation are linked inextricably to certain cell cycle events, in particular activation of cyclin-dependent kinases (CDKs). However, relatively few CDK targets driving these events have been uncovered.CP110, which is phosphorylated by CDKs in vitro and in vivo. Human CP110 localizes to centrosomes. Its expression is strongly induced at the G1-to-S phase transition, coincident with the initiation of centrosome duplication. RNAi-mediated depletion of CP110 indicates that this protein plays an essential role in centrosome duplication. Long-term disruption of CP110 phosphorylation leads to unscheduled centrosome separation and overt polyploidy. CP110 is a physiological centrosomal CDK target that promotes centrosome duplication, and its deregulation may contribute to genomic instability.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centriolar Coiled Coil Protein Of 110kDa (CCP110) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centriolar Coiled Coil Protein Of 110kDa (CCP110) Monoclonal Antibody Customized Service Offer
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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centriolar Coiled Coil Protein Of 110kDa (CCP110) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centriolar Coiled Coil Protein Of 110kDa (CCP110) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centriolar Coiled Coil Protein Of 110kDa (CCP110) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centriolar Coiled Coil Protein Of 110kDa (CCP110) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centriolar Coiled Coil Protein Of 110kDa (CCP110) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centriolar Coiled Coil Protein Of 110kDa (CCP110) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centriolar Coiled Coil Protein Of 110kDa (CCP110) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centriolar Coiled Coil Protein Of 110kDa (CCP110) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centriolar Coiled Coil Protein Of 110kDa (CCP110) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centriolar Coiled Coil Protein Of 110kDa (CCP110) ELISA Kit Customized Service Offer
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