ATXN7L3B belongs to the SGF11 family. Component of some SAGA transcription coactivator-HAT complex, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subcomplex required for histone deubiquitinylation. Interacts directly with ENY2 and USP22.
A putative ataxin-7 yeast orthologue (SGF73) has been identified recently as a new component of the SAGA (Spt/Ada/Gcn5 acetylase) multisubunit complex, a coactivator required for transcription of a subset of RNA polymerase II-dependent genes. ataxin-7 is the human orthologue of the yeast SAGA SGF73 subunit and is a bona fide subunit of the human TFTC-like transcriptional complexes. Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.
A putative ataxin-7 yeast orthologue (SGF73) has been identified recently as a new component of the SAGA (Spt/Ada/Gcn5 acetylase) multisubunit complex, a coactivator required for transcription of a subset of RNA polymerase II-dependent genes. ataxin-7 is the human orthologue of the yeast SAGA SGF73 subunit and is a bona fide subunit of the human TFTC-like transcriptional complexes. Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ataxin 7 Like Protein 3B (ATXN7L3B) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ataxin 7 Like Protein 3B (ATXN7L3B) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ataxin 7 Like Protein 3B (ATXN7L3B) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ataxin 7 Like Protein 3B (ATXN7L3B) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ataxin 7 Like Protein 3B (ATXN7L3B) | ELISA Kit Customized Service Offer |
- "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Genome-wide survey for biologically functional pseudogenes."PLoS Comput. Biol. 2:E46-E46(2006) [PubMed] [Europe PMC] [Abstract]