7-Ketodehydroepiandrosterone (7-Keto-DHEA)

7-Keto-DHEA is a steroid produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). 7-Keto is not directly converted to testosterone or estrogen, and has thus been investigated as a potentially more useful relative of DHEA. While in vitro and animal studies have suggested potential uses for 7-Keto in humans, there is currently insufficient scientific evidence to support its use as a weight-loss aid, muscle-builder, immune stimulant, or for any other clinical use. Nevertheless, 7-Keto is marketed as a dietary supplement with the implication that it may accelerate weight loss, increase metabolism, enhance memory, or prevent age-related changes. When used in a topical product 7-Keto caused long-lasting changes in the body's levels of testosterone, epitestosterone, estradiol, and other steroid hormones Researchers have raised concern that supplements may trigger positive tests for performance-enhancing drugs.