Biotin-Linked Polyclonal Antibody to Corticosterone (Cort)
Corticosrone
- Product No.LAA540Ge71
- Organism SpeciesPan-species (General) Same name, Different species.
- SourceAntibody labeling
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelBiotin
- Original Antibody PAA540Ge01-Polyclonal Antibody to Corticosterone (Cort)
- Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
- TraitsLiquid
- Concentration500µg/mL
- Organism Species MorePan-species (General)
- ApplicationsWB; IHC; ICC.
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 131
For more details, please contact local distributors! US$ 306 US$ 437 US$ 1093 US$ 4370
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against Cort. It has been selected for its ability to recognize Cort in immunohistochemical staining and western blotting.
USAGE
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine | Citations |
Respir Res. | Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats. PubMed: 20403205 |
Natural Product Sciences | Effects of Gypenosides on Acute Stress in Mice Papersearch: Source |
Neuropeptides.? | Role of adrenomedullin in the cerebrospinal fluid-contacting nucleus in the modulation of immobilization stress Pubmed:25911494 |
EXPERIMENTAL & CLINICAL CARDIOLOGY | Sick Sinus Syndrome May Attribute to the Decrease of ?±-klotho Protein in Mice Com:Source |
Journal of Pharmacological Sciences | Organ-Specific Activation of the Gastric Branch of the Efferent Vagus Nerve by Ghrelin in Urethane-Anesthetized Rats Pubmed:24366191 |
Toxicology Letters | Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic–pituitary–adrenal axis in adult male rats Pubmed:24440345 |
Stress. | Restraint stress alters immune parameters and induces oxidative stress in the mouse uterus during embryo implantation Pubmed:25238024 |
Int J Clin Exp Med | Diabetes alters the blood glucose response to ketamine in streptozotocin-diabetic rats PubMed: 26379948 |
Pakistan Veterinary Journal | Trivalent Chromium Attenuated Corticosterone Secretion and Actions in Adrenocorticotropic Hormone-Stimulated Rats In_Press: 15-058.Pdf |
BMC | Ameliorating effects of gypenosides on chronic stress-induced anxiety disorders in mice PubMed: 26370834 |
Behav Brain Res | Rats with differential self-grooming expression in the elevated plus-maze do not differ in anxiety-related behaviors PubMed: 26142783 |
Archives of Physiology and Biochemistry | Improvement of oral contraceptive-induced glucose dysreCavia (Guinea pig )lation and dyslipidemia by valproic acid is independent of circulating corticosterone Pubmed:26855320 |
Archives of Physiology and Biochemistry | Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder Pubmed:26934364 |
Neuroscience Letters | Electroacupuncture reCavia (Guinea pig )late hypothalamic–pituitary–adrenal axis and enhance hippocampal serotonin system in a rat model of depression Pubmed:26773866 |
Neural Regeneration Research | Moxibustion upreCavia (Guinea pig )lates hippocampal progranulin expression. Pubmed:27212922 |
Environmental Science and Pollution Research | Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway Pubmed:27102619 |
Eur Neuropsychopharmacol | Apelin-13 exerts antidepressant-like and recognition memory improving activities in stressed rats Pubmed:26853763 |
experimental brain research | Dopamine D2-like receptors modulate freezing response, but not the activation of HPA axis, during the expression of conditioned fear. pubmed:27766352 |
brain research bulletin | Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus. pubmed:28161195 |
Neurochemical Research | Effects of (-)-Sesamin on Chronic Stress-Induced Anxiety Disorders in Mice pubmed:27995494 |
Journal of Molecular Histology | Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea pubmed:29260435 |
Psychosomatic Medicine | The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure pubmed:28691995 |
Scientific Reports COMMUNICATIONS | Environmental perturbation of the circadian clock during pregnancy leads to transgenerational mood disorder-like behaviors in mice pubmed:28974783 |
BMC Gastroenterology | Role of serotonin on the intestinal mucosal immune response to stress-induced diarrhea in weaning mice pubmed:28633646 |
biorxiv | Anxiety-like but not despair-like behaviors are further aggravated by chronic mild stress in the early stages of APPswe/PS1dE9 transgenic mice doi.org/10.1101/202283 |
Frontiers in Molecular Neuroscience | Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. pubmed:28959186 |
Biochemical Pharmacology | Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats Pubmed:30028991 |
Toxicological Sciences | Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor a-Activated Kisspeptin Neurons 10.1093:toxsci |
Nutrition | Multigenerational effects of dietary macronutrients intake on the metabolic phenotype of male Wistar rats 10.1016:j.nut.2018.06.008 |
Behavioural Brain Research | Depressive-and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stress Pubmed:30012417 |
Stress | Blockade of AT1 type receptors for angiotensin II prevents cardiac microvascular fibrosis induced by chronic stress in Sprague–Dawley rats Pubmed:29676198 |
Inflammation | Differential Effects of Brain Death on Rat Microcirculation and Intestinal Inflammation: Female Male Pubmed:29737476 |
Respiratory physiology & neurobiology | Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathway Pubmed:29758366 |
Nature and Science of Sleep | Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at night Pubmed:30046256 |
Journal of Pharmacy and Pharmacology | Tannins from fruits attenuates GABA antagonist‐induced anxiety‐like behaviour modulation of neurotransmitters Pubmed: 30198561 |
Bulletin of Experimental Biology and Medicine | Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in … Pubmed: 30353332 |
Brain, Behavior, and Immunity | HMGB1-Mediated Differential Response on Hippocampal Neurotransmitter Disorder and Neuroinflammation in Adolescent Male and Female Mice following Cold Exposure Pubmed: 30476565 |
Heliyon | Establishment and evaluation of a novel mouse model of peri/postmenopausal depression Doi: 10.1016/j.heliyon.2019.e01195 |
Scientific Reports | Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive-and anxiety-like behaviour, and gut microbiome composition Pubmed: 31015500 |
Food & Function | Antidepressant-like effects of dietary gardenia blue pigment derived from genipin and tyrosine Doi: 10.1039/C9FO00480G |
Neuroscience Letters | Synaptic structure and alterations in the hippocampus in neonatal rats exposed to lipopolysaccharide Pubmed: 31288048 |
FASEB Journal | Contribution of DNA methylation in chronic stress–induced cardiac remodeling and arrhythmias in mice Pubmed: 31431066 |
Cells | MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model Pubmed: 31540304 |
endocrine journal | Mice with nucleus tractus solitarius injury induced by chronic restraint stress present impaired ability to raise blood glucose and glucagon levels when blood glucose … Pubmed: 32249244 |
INTERNATIONAL IMMUNOPHARMACOLOGY | GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and … Pubmed: 33166810 |
neurochemical research | Anxiolytic and Anti‑depressive Like Effects of Translocator Protein (18 kDa) Ligand YL‑IPA08 in a Rat Model of Postpartum Depression Pubmed: 32383026 |
BioMed Research International | Pathophysiological Changes in Female Rats with Estrous Cycle Disorder Induced by Long-Term Heat Stress Pubmed: 32685488 |
博士论文 | Neurobiological determinants of depressive-like symptoms in rodents |
Behavioral Ecology and Sociobiology | Exposure to eagle owl feces induces anti-predator behavior, physiology, and hypothalamic gene responses in a subterranean rodent, the plateau zokor (Eospalax … |
Ther Adv Chronic Dis | Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice 33294147 |
International Journal of?Nanomedicine | Water-Soluble Carbon Dots in Cigarette Mainstream Smoke: Their Properties and the Behavioural, Neuroendocrinological, and Neurotransmitter Changes They ¡ 33762821 |
CRYOBIOLOGY | O-GlcNAc/Akt pathway regulates glucose metabolism and reduces apoptosis in liver of piglets with acute cold stress 33651993 |
NEUROSCIENCE RESEARCH | Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats 33785408 |
Biomed Res Int | A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating … Pubmed:35281603 |
Ecotoxicol Environ Saf | Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stress Pubmed:35588616 |
Catalog No. | Related products for research use of Pan-species (General) Organism species | Applications (RESEARCH USE ONLY!) |
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MEA540Ge | Mini Samples ELISA Kit for Corticosterone (Cort) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CCA540Ge | CLIA Kit for Corticosterone (Cort) | Chemiluminescent immunoassay for Antigen Detection. |
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KSA540Ge11 | ELISA Kit DIY Materials for Corticosterone (Cort) | Main materials for "Do It (ELISA Kit) Yourself". |