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Polyclonal Antibody to Thyroid Stimulating Hormone (TSH)
Thyrotropin
- Product No.PAA463Hu09
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourcePolyclonal antibody preparation
- HostRabbit
- Potencyn/a
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelNone
- Immunogen n/a
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- TraitsLiquid
- Concentration500µg/mL
- Organism Species Moren/a
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 81
US$ 189
US$ 270
US$ 675
US$ 2700
For more details, please contact local distributors!
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against TSH. It has been selected for its ability to recognize TSH in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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| Magazine | Citations |
| Blood | Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID Pubmed: 22184407 |
| Life Science Journal | Can Nigella Sativa oil (NSO) reverse hypothyroid status induced by PTU in rat? biochemical and histological studies Lifesciencesite: Source |
| Thyroid | Impact of Metformin and Compound C on NIS expression and iodine uptake in vitro and in vivo: a role for CRE in AMPK modulation of thyroid function Pubmed: 23819433 |
| Journal of Functional Foods | Effect of lettuce biofortified with iodine by soil fertilization on iodine concentration in various tissues and selected biochemical parameters in serum of Wistar rats Sciencedirect:S1756464615000894 |
| J Endocrinol. | Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis Pubmed:24928937 |
| journal of lipid research | Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver PubMed: 25713102 |
| Int J Clin Exp Med | Lead exposure causes thyroid abnormalities in diabetic rats PubMed: 26221254 |
| Jubilant Drax Image | Perinatal Iron Deficiency-Induced Hypothyroxinemia Impairs Early Brain Development Regardless of Normal Iron Levels in the Neonatal Brain Pubmed:27231981 |
| PLoS One. | The Impact of Carrot Enriched in Iodine through Soil Fertilization on Iodine Concentration and Selected Biochemical Parameters in Wistar Rats Pubmed:27043135 |
| journal of bone and mineral research | Knock-In of the Recurrent R368X Mutation of PRKAR1A that Represses cAMP-Dependent Protein Kinase A Activation: A Model of Type 1 Acrodysostosis. pubmed:27589370 |
| Toxicological Sciences | Exposure of pregnant mice to perfluorobutanesulfonate causes hypothyroxinemia and developmental abnormalities in female offspring pubmed:27803384 |
| Sci Rep | Exposure of pregnant mice to triclosan impairs placental development and nutrient transport. pubmed:28322267 |
| Bulletin of the World Health Organization | Endemic goitre in the Sudan despite longstanding programmes for the control of iodine deficiency disorders handle:123456789 |
| International Journal of Peptide Research and Therapeutics | Effect of Intracerebroventricular Administration of Apelin-13 on the Hypothalamus–Pituitary–Thyroid Axis and Peripheral Uncoupling Proteins article:10.1007 |
| Tropical Journal of Pharmaceutical Research | Neuroprotective effects of thymoquinone against cerebellar histopathological changes in propylthiouracil-induced hypothyroidism in adult rats 10.4314/tjpr.v16i5.9 |
| 30 | The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. pubmed:28546511 |
| NITRIC OXIDE-BIOLOGY AND CHEMISTRY | Voluntary exercise training restores anticontractile effect of NO in coronary arteries of adult rats with antenatal/early postnatal hypothyroidism Pubmed:29307633 |
| Environmental Pollution | Prenatal exposure to polychlorinated biphenyl and umbilical cord hormones and birth outcomes in an island population Pubmed:29525625 |
| Frontiers in Molecular Neuroscience | Impact of Triclosan on Female Reproduction through Reducing Thyroid Hormones to Suppress Hypothalamic Kisspeptin Neurons in Mice Pubmed:29403355 |
| Neuroscience Letter | Central irisin administration suppresses thyroid hormone production but increases energy consumption in rats Pubmed:29574218 |
| Journal of Neuroinflammation | Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice Pubmed: 30373627 |
| Cell Reports | Zika Virus Infection in Hypothalamus Causes Hormone Deficiencies and Leads to Irreversible Growth Delay and Memory Impairment in Mice Pubmed: 30404008 |
| Journal of Diabetes Research | The Adverse Effects of Thyrotropin Absence on Pancreatic β Cell Function in Mice |
| Endocrine | Hypothyroidism-related zinc deficiency leads to suppression of T lymphocyte activity Pubmed: 31056723 |
| Oxidative Medicine and Cellular Longevity | Oxidative Stress Produced by Hyperthyroidism Status Induces the Antioxidant Enzyme Transcription through the Activation of the Nrf-2 Factor in Lymphoid Tissues of … |
| Reproductive Biology and Endocrinology | Hashimoto's thyroiditis impairs embryo implantation by compromising endometrial morphology and receptivity markers in euthyroid mice Pubmed: 31729993 |
| Gli | Tanycyte ablation in the arcuate nucleus and median eminence increases obesity susceptibility by increasing body fat content in male mice Pubmed: 32173924 |
| Clinical Immunology | The role of protein disulphide-isomerase A3 as autoantigen in the pathogenesis of autoimmune thyroiditis and related brain damage in adult mice Pubmed: 31982645 |
| Nature | Feeding induces cholesterol biosynthesis via the mTORC1–USP20–HMGCR axis Pubmed: 33177714 |
| Thyroid | Generation and Characterization of a New Resistance to Thyroid Hormone Mouse Model with Thyroid Hormone Receptor Alpha Gene Mutation Pubmed: 32924834 |
| Thyroid | Hashimoto's thyroiditis induces hippocampus-dependent cognitive alterations by impairing astrocytes in euthyroid mice Pubmed: 32907517 |
| Int Immunopharmacol | Experimental evidence for alpha enolase as one potential autoantigen in the pathogenesis of both autoimmune thyroiditis and its related encephalopathy Pubmed: 32442899 |
| Brazilian Journal of Development | Maternal exposure of triclosan causes fetal development restriction and female reproductive alterations in rat offspring/A exposição materna ao triclosan causa … |
| Comparaison des marqueurs hormonaux et histomorphométriques chez la souris un modèle d'hypothyroïdie après 28 jours de traitement au PTU par voie alimentaire. | |
| Andrologia | Thyroid hormones, Sertoli cell proliferation and differentiation in progenies from carbamazepine©\treated rat dams during pregnancy and lactation 33433934 |
| INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart 33375430 |
| Biomedicines | Role of Kallikrein 7 in Body Weight and Fat Mass Regulation. Biomedicines 2021, 9, 131 33572949 |
| Mol Neurobiol | Maternal Subclinical Hypothyroidism in Rats Impairs Spatial Learning and Memory in Offspring by Disrupting Balance of the TrkA/p75 NTR Signal Pathway 33966253 |
| Clin Epigenetics | Genome?wide profiling of DNA methylation and gene expression unravel the epigenetic landscape in diabetes-related hypothyroidism 34092241 |
| Pharmaceutics | Improved Therapeutic Efficiency against Obesity through Transdermal Drug Delivery Using Microneedle Arrays |
| BRITISH JOURNAL OF NUTRITION | Effects of iodine excess on serum thyrotropin-releasing hormone levels and type 2 deiodinase in the hypothalamus of Wistar rats 34250878 |
| Gene Therapy | Correction of a knock-in mouse model of acrodysostosis with gene therapy using a rAAV9-CAG-human PRKAR2A vector 34599290 |
| NatCommun | Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis 34876572 |
| Int J Mol Sci | The Deubiquitinase OTUB1 Is a Key Regulator of Energy Metabolism Pubmed:35163456 |
| Molecular Biology Reports | Effects of meteorin-like hormone on endocrine function of hypothalamo-hypophysial system and peripheral uncoupling proteins in rats Pubmed:35332411 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| SPA463Hu02 | Synthetic Thyroid Stimulating Hormone (TSH) | Immunogen; Blocking Peptide. |
| CPA463Hu21 | OVA Conjugated Thyroid Stimulating Hormone (TSH) | Immunogen; SDS-PAGE; WB. |
| CPA463Hu22 | OVA Conjugated Thyroid Stimulating Hormone (TSH) | Immunogen; SDS-PAGE; WB. |
| PAA463Hu01 | Polyclonal Antibody to Thyroid Stimulating Hormone (TSH) | WB; IHC; ICC; IP. |
| PAA463Hu08 | Polyclonal Antibody to Thyroid Stimulating Hormone (TSH) | WB; IHC; ICC; IP. |
| PAA463Hu09 | Polyclonal Antibody to Thyroid Stimulating Hormone (TSH) | WB; IHC; ICC; IP. |
| IEA463Hu | Instant ELISA Kit for Thyroid Stimulating Hormone (TSH) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEA463Hu | ELISA Kit for Thyroid Stimulating Hormone (TSH) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| CEA463Hu | ELISA Kit for Thyroid Stimulating Hormone (TSH) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA463Hu | Multiplex Assay Kit for Thyroid Stimulating Hormone (TSH) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |
| KSA463Hu11 | ELISA Kit DIY Materials for Thyroid Stimulating Hormone (TSH) | Main materials for "Do It (ELISA Kit) Yourself". |