Polyclonal Antibody to Melatonin (MT)
N-Acetyl-5-Methoxytryptamine
- Product No.PAA908Ge01
- Organism SpeciesPan-species (General) Same name, Different species.
- SourcePolyclonal antibody preparation
- HostRabbit
- Potencyn/a
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelNone
- Immunogen CPA908Ge11-BSA Conjugated Melatonin (MT)
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- TraitsLiquid
- Concentration0.5mg/ml
- Organism Species MorePan-species (General)
- ApplicationsELISA, CLIA. / IHC-Fr, ICC, IP (predicted).
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 176
For more details, please contact local distributors! US$ 412 US$ 588 US$ 1470 US$ 5880
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against MT. It has been selected for its ability to recognize MT in ELISA and CLIA.
USAGE
Enzyme-Linked Immune Sorbent Assay: 1µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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INCREMENT SERVICES
Magazine | Citations |
Domestic Animal Endocrinology | Effects of melatonin on islet neogenesis and beta cell apoptosis in streptozotocin-induced diabetic rats: an immunohistochemical study ScienceDirect: S0739724012000112 |
General Assembly and Scientific Symposium | Biomarkers inducing changes due to microwave exposure effect on rat brain Academin: Source |
Chinese Journal | Comparison of the flow characteristics for the honeycomb and labyrinth seal using numerical simulation Cnki: Source |
Clinics (Sao Paulo). | The therapeutic effect of a pulsed electromagnetic field on the reproductive patterns of male Wistar rats exposed to a 2.45-GHz microwave field PubMed: 21876981 |
Journal of Radiation Research | Effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on serum hormone levels in rats PubMed: 23239176 |
Experimental Gerontology | Improvement of oxidative stress and immunity by melatonin: An age dependent study in golden hamster Pubmed: 23220117 |
Journal of Human Reproductive Sciences | Melatonin and its correlation with testosterone in polycystic ovarian syndrome NCBI: PMC3963309 |
Indian Journal of Experimental Biology | Daily variation in melatonin level, antioxidant activity and general immune response of peripheral blood mononuclear cells and lymphoid tissues of Indian goat Capra … Pubmed: 24851409 |
Metabolic Syndrome | Serum Melatonin Level Disturbance is Related to Metabolic Syndrome and Subclinical Arterial Dysfunction in Shift Working Healthy Men Researchgate: Source |
Israel Journal of Veterinary Medicine | Melatonin Administration Aids Bone Healing in Diabetic Rats Ijvm: Source |
Journal of Photochemistry and Photobiology B: Biology | Photoperiodic induced melatonin regulates immunity and expression pattern of melatonin receptor MT1 in spleen and bone marrow mononuclear cells of male golden hamster. Pubmed: 24090924 |
In Vivo. | Influence of?circadian?time?and lighting conditions on expression of melatonin?receptors?1?and?2?in?murinelymphocytes. Pubmed:25189896 |
Biomicrofluidics. | Molecularly imprinted electrochemical sensing of urinary melatonin in a microfluidic system Pubmed:25584113 |
International Journal of Advanced Research | Localization and expression of androgen receptor (AR) and melatonin membrane receptor (MT1R) in accessory sex organs of adult male golden hamster, Mesocricetus auratus: Modulation by photoperiod. Com:Source |
Journal of Nanoparticle Research | Titanium oxide (TiO2) nanoparticles in induction of apoptosis and inflammatory response in brain Springer:Source |
International Immunopharmacology | MT1 receptor expression and AA-NAT activity in lymphatic tissue following melatonin administration in male golden hamster Pubmed:25023124 |
Journal of Photochemistry and Photobiology B: Biology | Photoperiodic regulation of melatonin membrane receptor (MT1R) expression and steroidogenesis in testis of adult golden hamster, Mesocricetus auratus Pubmed:25255424 |
Andrologia | Melatonin prevents dexamethasone-induced testicular oxidative stress and germ cell apoptosis in golden hamster, Mesocricetus auratus Pubmed:25277062 |
Biological Rhythm Research | Reproductive seasonality in the Indian pygmy field mouse, Mus terricolor Tandfonline:Source |
Acta Histochem | Developmental changes of melatonin receptor expression in the spleen of the chicken, Gallus domesticus PubMed: 26024931 |
Acta Histochemica | Melatonin modulates monochromatic light-induced GHRH expression in the hypothalamus and GH secretion in chicks Pubmed:26948666 |
Veterinary Word | Effect of extended photoperiod during winter on growth and onset of puberty in Murrah buffalo heifers Pubmed:27051212 |
Journal of Photochemistry and Photobiology B: Biology | Effect of melatonin on monochromatic light-induced T-lymphocyte proliferation in the thymus of chickens Pubmed:27203566 |
Asian-Australas J Anim Sci. | Effect of Monochromic Light-emitting Diode Light with Different Color on the Growth and ReproductivePerformances of Breeder Geese. Pubmed:26954165 |
Revista Brasileira de Saúde e Produção Animal | Desempenho e comportamento de suínos em fase de terminação submetidos a diferentes programas de luz S1519-99402016000200272 |
journal of neuroendocrinology | Green light inhibits GnRH-I expression by stimulating the melatonin-GnIH pathway in the chick brain. pubmed:28295740 |
Revista Brasileira de Medicina do Esporte | EFFECTS OF DIURNAL AND NOCTURNAL STRENUOUS EXERCISE ON SERUM MELATONIN LEVELS S1517-86922016000600436 |
Journal of Photochemistry and Photobiology B | Role of monochromatic light on daily variation of clock gene expression in the pineal gland ofchick. pubmed:27643985 |
Journal of Oral Science | Antioxidant effects of melatonin in heart tissue after induction of experimental periodontitis inrats. pubmed:28367898 |
畜牧兽医学报 | 单色绿光对鸡胚褪黑激素合成的影响 DOI: 10.11843/j.issn.0366-6964.2017.05.019 |
Oxidative Medicine and Cellular Longevity | Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet pubmed:29142618 |
Pakistan veterinary journal | Inhibitory Effect of Melatonin on Formation of the Chicken Primordial Follicles. ISSN: 0253-8318 |
Acta histochemica | Melatonin modulates monochromatic light-induced melatonin receptor expression in the hypothalamus of chicks pubmed:28943001 |
Stem Cell Reviews and Reports | A Circadian Rhythm in both Complement Cascade (ComC) Activation and Sphingosine-1-Phosphate (S1P) Levels in Human Peripheral Blood Supports a … 10.1007:s12015-018-9836-7 |
Photochemistry and Photobiology | Effect of Monochromatic Light on Circadian Rhythm of Clock Genes in Chick Pinealocytes Pubmed:29896808 |
Reproduction In Domestic Animals | Expression of melatonin and its related synthase and membrane receptors in the oestrous corpus luteum and corpus luteum verum of sheep Pubmed:29943511 |
OCCUPATIONAL HYGIENE–PERFORMANCE COFACTOR IN POWER ENGINEERING. BIOCHEMICAL RESPONSE TO EXPOSURE TO EXTREMELY LOW … id:PLUMEE201601V06S01A0004 | |
Asian Spine Journal | A Comparative Analysis of the Metabolic and Coagulative Profiles in Patients with Idiopathic Scoliosis, Congenital Scoliosis and Healthy Controls: A Case … Pubmed: 30322254 |
Endocrine Connections | cBmal1 but not cClock is associated with monochromatic green light-induced circadian rhythm of melatonin in chick pinealocytes Pubmed: 30533004 |
Reproductive biology and endocrinology | Profile of melatonin and its receptors and synthesizing enzymes in cumulus–oocyte complexes of the developing sheep antral follicle—a potential estradiol … Pubmed: 30606208 |
Chronobiology international | Effect of pinealectomy on the circadian clock of the chick retina under different monochromatic lights Pubmed: 30663441 |
Journal of Pineal Research | Plasma levels of melatonin in dilated cardiomyopathy Pubmed: 30715754 |
Journal of Clinical Medicine | Elevated Serum Melatonin under Constant Darkness Enhances Neural Repair in Spinal Cord Injury through Regulation of Circadian Clock Proteins Expression Pubmed: 30678072 |
Brain, Behavior, and Immunity | Melatonergic agonist regulates circadian clock genes and peripheral inflammatory and neuroplasticity markers in patients with depression and anxiety |
International Journal of Molecular Sciences | Mel1c Mediated Monochromatic Light-Stimulated IGF-I Synthesis through the Intracellular Gαq/PKC/ERK Signaling Pathway Pubmed: 30987295 |
Journal of Pineal Research | Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice Pubmed: 30929267 |
PLoS One | Melatonin mediates monochromatic green light-induced satellite cell proliferation and muscle growth in chick embryo Pubmed: 31059537 |
Immunology Letters | Effect of the melatonin nuclear receptor RORα on monochromatic light-induced T-lymphocyte proliferation in chicken thymus Pubmed: 31326445 |
Journal of photochemistry and photobiology. B, Biology | Effect of melatonin on monochromatic light-induced changes in clock gene circadian expression in the chick liver Pubmed: 31247384 |
Life sciences | Melatonin maintains mitochondrial membrane potential and decreases excessive intracellular Ca2+ levels in immature human oocytes Pubmed: 31472147 |
Journal of Clinical Medicine | Conditional Controlled Light/Dark Cycle Influences Exercise-Induced Benefits in a Rat Model with Osteoarthritis: In Vitro and In Vivo Study Pubmed: 31684092 |
experimental eye research | Effect of monochromatic light on the circadian clock of cultured chick retinal tissue Pubmed: 32198015 |
Medicine | Saliva cortisol, melatonin levels and circadian rhythm alterations in Chinese primary school children with dyslexia Pubmed: 32028434 |
pharmaceutical biology | Role of melatonin in intestinal mucosal injury induced by restraint stress in mice Pubmed: 32298156 |
FISH PHYSIOLOGY AND BIOCHEMISTRY | Hypoxia-mediated inhibition of cholesterol synthesis leads to disruption of nocturnal sex steroidogenesis in the gonad of koi carp, Cyprinus carpio Pubmed: 33034795 |
INFLAMMATION RESEARCH | Sleep deprivation aggravated lipopolysaccharide/d-galactosamine-induced acute liver injury by suppressing melatonin production Pubmed: 32809047 |
Journal of Health Sciences and Medicine | Effects of tryptophan, a precursor for melatonin, on IVF outcomes and Doppler parameters |
急性睡眠剥夺对小鼠血浆褪黑激素水平和下丘脑钟基因表达的影响 | |
Influence of phytomelatonin on immune cell function in male golden hamsters | |
Horm Mol Biol Clin Investig | Investigation of the effect of training on serotonin, melatonin and hematologic parameters in adolescent basketball players 34090322 |
Frontiers in Cell and Developmental Biology | Melatonin Promotes Heterotopic Ossification Through Regulation of Endothelial-Mesenchymal Transition in Injured Achilles Tendons in Rats 33644068 |
Oxidative Medicine and Cellular Longevity | A Green and Blue Monochromatic Light Combination Therapy Reduces Oxidative Stress and Enhances B-Lymphocyte Proliferation through Promoting ¡ 33828639 |
International Journal of General Medicine | Identification of Serotonin as a Predictive Marker for Breast Cancer Patients 34045888 |
Physiological crosstalk between the Mel1a and Mel1c pathways modulates melatonin-mediated, monochromatic light combination-induced bursa B-lymphocyte?¡ | |
Exp Neurol | MiR-375-3p mediates reduced pineal function in hypoxia-ischemia brain damage 34280452 |
Oxid Med Cell Longev | Parameters of Oxidative Stress, Vitamin D, Osteopontin, and Melatonin in Patients with Lip, Oral Cavity, and Pharyngeal Cancer 34721756 |
Antioxidants | Melatonin Nuclear Receptors Mediate Green-and-Blue-Monochromatic-Light-Combinations-Inhibited B Lymphocyte Apoptosis in the Bursa of Chickens via … Pubmed:35453433 |
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