Packages (Simulation)
Quality Guarantee
Instruction Manual
Certificate
Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42)
- Product No.PAA946Ra01
- Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- SourcePolyclonal antibody preparation
- HostRabbit
- Potencyn/a
- Ig Type IgG
- PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
- LabelNone
- Immunogen n/a
- Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
- TraitsLiquid
- Concentration0.5mg/mL
- Organism Species Moren/a
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies. - DownloadInstruction Manual
- UOM 20µl100µl 200µl 1ml 10ml
- FOB
US$ 103
US$ 239
US$ 342
US$ 855
US$ 3420
For more details, please contact local distributors!
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against Ab1-42. It has been selected for its ability to recognize Ab1-42 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
| Magazine | Citations |
| Neuropsychopharmacology | Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease Pubmed: 23493042 |
| Neuropharmacology and analgesia | The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1–42 seeding and short-term memory deficits in the Aβ25–35 mouse model of Alzheimer's disease Pubmed: 23123349 |
| 世界科技研究与发展(World Sci-tech R & D) | 慢病毒介导的ＣＢＳ基因过表达对原代皮质神经元 Globesci:Source |
| 南方医科大学学报 | 外源性硫化氢对高糖条件下原代神经元β淀粉样蛋白的影响 J-Smu:Source |
| Neurochemical research | Effects of Aluminium on β-Amyloid (1–42) and Secretases (APP-Cleaving Enzymes) in Rat Brain Pubmed:24792732 |
| Indian J Biochem Biophys. | Amyloid ? lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity Pubmed:25296496 |
| Cell Mol Neurobiol | Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells PubMed: 25809614 |
| Neuropsychiatr Dis Treat | Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex PubMed: 26316755 |
| Neurochem Int | Geniposide attenuates insulin-deficiency-induced acceleration of β-amyloidosis in an APP/PS2 transgenic model of Alzheimer's disease PubMed: 25882166 |
| Journal of Alzheimer’s Parkinsonism & Dementia | The Potential Effect of Epigallocatechin-3-Gallate alone or in Combination with Vitamin E and Selenium on Alzheimer's Disease Induced by Aluminum in Rats open-access: |
| 世界科技研究与发展 | 芝麻素对高糖条件下PC12细胞Aβ和BACE-1表达的影响 article:10299 |
| Am J Alzheimers Dis Other Demen. | Tong Luo Jiu Nao, a Chinese Medicine Formula, Reduces Inflammatory Stress in a Mouse Model of Alzheimer's Disease Pubmed:26993489 |
| Світ медицини та біології | ОСОБЕННОСТИ ПРОЦЕССОВ ФОРМИРОВАНИЯ ПОКАЗАТЕЛЕЙ ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ ВЫСШЕЙ НЕРВНОЙ ДЕЯТЕЛЬНОСТИ И ХАРАКТЕРИСТИКИ ВНИМАНИЯ СТУДЕНТОВ SMB-2016-03-062.pdf |
| 世界科技研究与发展 | 芝麻素对高糖条件下PC12 细胞Aß 和BACE 1 表达的影响 QK:92621A |
| Archives of Pharmacal Research | Geniposide attenuates the level of Aβ1–42 via enhancing leptin signaling in cellular and APP/PS1 transgenic mice pubmed:28160136 |
| Food Funct. | Effects of dietary glucocerebrosides from sea cucumber on the brain sphingolipid profiles of mouse models of Alzheimer's disease. pubmed:28232989 |
| Scientific Reports | Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease articles:srep41041.ris |
| Journal of Medicinal Food | Cerebrosides from Sea Cucumber Protect Against Oxidative Stress in SAMP8 Mice and PC12 Cells pubmed:28406733 |
| Journal of Nutritional Biochemistry | Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet Pubmed:29986309 |
| Biochemical Pharmacology | Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats Pubmed:30028991 |
| Journal of Affective Disorders | Sub-chronic celecoxib prevents soluble beta amyloid-induced depressive-like behaviour in rats Pubmed:29879605 |
| Biomedicine & Pharmacotherapy | Punicalagin ameliorates the elevation of plasma homocysteine, amyloid-β, TNF-α and apoptosis by advocating antioxidants and modulating apoptotic mediator proteins in brain modulating apoptotic mediator … Pubmed:29579708 |
| Journal of Agricultural and Food Chemistry | Effects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer's Disease in APP/PS1 Double-Transgenic Mice Pubmed:29695154 |
| Neurotoxicology | Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats Pubmed:29522778 |
| Biochemical and Biophysical Research Communications | CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease Pubmed:29777699 |
| Oncotarget | Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse … Pubmed:29731975 |
| Experimental and Therapeutic Medicine | Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β‑amyloid production and tau hyperphosphorylation Doi: 10.3892/etm.2018.6860 |
| 非编码RNA miR-137 调控tau 蛋白磷酸化和L 型钙离子通道CACNA1C 参与阿尔茨海默病的发生 | |
| 台湾农业研究 | (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探 |
| The Efficacy of Sauropus androgynus Leaves Extract To Improve Cognitive Function in Wistar Rats Induced Alzheimer's | |
| Neurotoxicity Research | Effect of Aluminum-Maltolate on the Content of Aβ Protein and the Expression of ApoER2, VLDLRs, and LRP1 in PC12-ApoE4 Cells Pubmed: 30649678 |
| Neurochemical Research | Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation Pubmed: 30756214 |
| Molecular and Cellular Biochemistry | Repetitive transcranial magnetic stimulation protects mice against 6-OHDA-induced Parkinson's disease symptoms by regulating brain amyloid β level |
| PLoS One | Obstructive sleep apnea may increase the risk of Alzheimer's disease Pubmed: 31487291 |
| Metabolic Brain Disease | Nanoformulated ellagic acid ameliorates pentylenetetrazol-induced experimental epileptic seizures by modulating oxidative stress, inflammatory cytokines and … Pubmed: 31728888 |
| 博士论文 | Neurobiological determinants of depressive-like symptoms in rodents |
| Pharmacognosy Magazine | Mahanimbine-induced neuroprotection via cholinergic system and attenuated amyloidogenesis as well as neuroinflammation in lipopolysaccharides-induced … |
| biosciences biotechnology research asia | Dietary Malted Barley Grain Improved Structure and Function of Spinal Cord of Mother Rats fed on a high cholesterol diet. |
| Neurochem Res | Ex Vivo Investigation of Bexarotene and Nicotinamide Function as a Protect?ve Agent on Rat Synaptosomes Treated with A¦Â (1-42) 33428094 |
| Food Funct | Comparative study on the effects of phosphatidylserine rich in DHA and EPA on A¦Â-intervened Alzheimer's disease using cell models 33876786 |
| Int J Neurosci | Protective effects of repetitive transcranial magnetic stimulation against 6-OHDA-induced Parkinson's symptoms in a mice model: the key role of miR-409-3p/PDHB ¡ 34078216 |
| Brain Res Bul | Immunization with A¦Â3-10-KLH vaccine improves cognitive function and ameliorates mitochondrial dysfunction and reduces Alzheimer's disease-like pathology in Tg ¡ 34044034 |
| PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | The effect of a 6-month Ketogenic Medium-Chain Triglyceride Supplement on Plasma Cardiometabolic and Inflammatory Markers in Mild Cognitive?¡ 33906081 |
| Crystals | Potential Therapeutic Effects of New Ruthenium (III) Complex with Quercetin: Characterization, Structure, Gene Regulation, and Antitumor and Anti-Inflammatory Studies (RuIII/Q Novel Complex Is a Potent Immunoprotective Agent) |
| Neurosci Lett | GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal 34695452 |
| Arch Gerontol Geriatr | The influence of vinpocetine alone or in combination with Epigallocatechin-3-gallate, Coenzyme COQ10, Vitamin E and Selenium as a potential neuroprotective … 34706318 |
| Metab Brain Dis | Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … Pubmed:35312928 |
| Medicinal Chemistry Research | New Thienopyridine Scaffold as An Antidementia Lead: In Silico Study and Biological Screening |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| CPA946Ra11 | BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) | Immunogen; SDS-PAGE; WB. |
| CPA946Ra21 | OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) | Immunogen; SDS-PAGE; WB. |
| CPA946Ra31 | KLH Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) | Immunogen; SDS-PAGE; WB. |
| PAA946Ra01 | Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) | WB; IHC; ICC; IP. |
| LAA946Ra71 | Biotin-Linked Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) | WB; IHC; ICC. |
| CEA946Ra | ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA946Ra | Multiplex Assay Kit for Amyloid Beta Peptide 1-42 (Ab1-42) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |