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Recombinant Copeptin (CPP)

C-Terminal Provasopressin; Vasopressin-Neurophysin 2-Copeptin

  • Product No.RPA365Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass34.2kDa
  • Accurate Molecular Mass37kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla130~Tyr168 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point10.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 144  US$ 360  US$ 720  US$ 2160  US$ 5400 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Med-Science. Copeptin: May it be a novel biomarker for insulin theraphy in diabetes? An animal study. Ejmanager: Source
Psychiatry and Clinical Neurosciences Serum copeptin in children exposed to maltreatment Pubmed:27278269
United States Patent Application Methods for Diagnosis and Treatment of Concussion or Brain Injury 2016:0103140
J Physiol Role of enteroendocrine L‐cells in arginine vasopressin‐mediated inhibition of colonic anion secretion Pubmed:27037495
International Journal of Clinical and Experimental Medicine Can hypoxia enhance sexual arousal?-Molecular-biological analysis of the hypothalamus in male rats placed with oestrous female rats under hypoxic … files:ijcem0031358.pdf
Front Physiol Orthostatic Challenge Shifts the Hemostatic System of Patients Recovered from Stroke toward Hypercoagulability. pubmed:28223937
Kidney Blood Pressure Research N-Terminal Prohormone of Brain Natriuretic Peptide but not C-Terminal Pre-Pro Vasopressin (Copeptin) Level is Associated with the Response to Antihypertensive … pubmed:29190613
Hindawi Publishing Corporation Early Prediction of Preeclampsia journals:297397
Journal of Urology Evaluation of Urinary Aquaporin 2 and Plasma Copeptin as Biomarkers of Effectiveness of Desmopressin Acetate for the Treatment of Monosymptomatic Nocturnal Enuresis. pubmed:28457803
American Journal of Physiology-Renal Physiology Experimental Heat Stress Nephropathy and Liver Injury are Improved by Allopurinol Pubmed:29667911
American Journal of Physiology-Regulatory Integrative and Comparative Physiology Angiotensin AT Receptors Expressed in Vasopressin-Producing Cells of the Supraoptic Nucleus Contribute to the Osmotic Control of Vasopressin Pubmed:29364700
BMC Nephrology Rehydration with fructose worsens dehydration-induced renal damage Pubmed:30005632
Experimental and Therapeutic Medicine Copeptin level in the early prediction of cardiorenal syndrome in rats Pubmed:30112047
中国病理生理杂志 和肽素水平对大鼠心肾综合征的早期预测价值 filename:ZBLS201802013
Hypertension Abstract P311: Static Urine Osmolality With Elevated First Trimester Urine Copeptin in Human Preeclampsia
Journal of Pediatric Urology Assessment of serum levels of copeptin and corticotropin-releasing factor in children with monosymptomatic and nonmonosymptomatic nocturnal enuresis
experimental physiology Cognitive performance is associated with cerebral oxygenation and peripheral oxygen saturation, but not plasma catecholamines, during graded normobaric hypoxia
international urology and nephrology Dialysate copeptin and peritoneal transport in incident peritoneal dialysis patients Pubmed: 31187425
American Journal of Physiology-renal Physiology The contribution of collecting duct NOS1 to the concentrating mechanisms in male and female mice Pubmed: 31241990
american journal of physiology-renal physiology The increase of core temperature affected the progression of kidney injury by repeated heat stress exposure Pubmed: 31390229
Scientific Reports Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion Pubmed: 31863073
BMC Nephrology Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5 Pubmed: 32033584
Archives of Biochemistry and Biophysics Micro RNA 146a gene variant/TNF-α/IL-6/IL-1 β; A cross-link axis inbetween oxidative stress, endothelial dysfunction and neuro-inflammation in acute ischemic stroke … Pubmed: 31738890
Ann Nutr Metab Copeptin and Nesfatin-1 Are Interrelated Biomarkers with Roles in the Pathogenesis of Insulin Resistance in Chinese Children with Obesity Pubmed: 33027789
Biomolecules . Multimarker Approach to Identify Patients with Coronary Artery Disease at High Risk for Subsequent Cardiac Adverse Events: The Multi-Biomarker Study Pubmed: 32549327
Arch Med Res Relation of Copeptin with Diabetic and Renal Function Markers Among Patients with Diabetes Mellitus Progressing Towards Diabetic Nephropathy Pubmed: 32505416
河北医科大学学报 重组人脑利钠肽治疗慢性肺心病急性加重期的临床效果及对5-HT 浓度的影响
Scientific reports Validity of different copeptin assays in the differential diagnosis of the polyuria-polydipsia syndrome 33980941
International Journal of Women¡¯s Health and Reproduction Sciences Are the Circulating Levels of Copeptin and Fibronectin Dysregulated in Preeclamptic South African Black Women?
Dicle T?p Dergisi Copeptin levels are more elevated and associated with cardiovascular events in the unity of chronic ischemic heart and chronic kidney diseases
High serum copeptin may be a marker of an increased carotid intima-media thickness in asymptomatic patients with type 1 diabetes.
Nutrients The Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose
Acta Physiol (Oxf) Dietary K+ acts as a genuine diuretic Pubmed:34984847
Anal Chim Acta Spectrally multiplexed assay using gap enhanced nanoparticle for detection of a myocardial infarction biomarker panel Pubmed:35190126
J Cell Physiol Arcuate NPY is involved in salt‐induced hypertension via modulation of paraventricular vasopressin and brain‐derived neurotrophic factor Pubmed:35312067
Children Copeptin Concentrations in Plasma of Healthy Neonates in Relation to Water–Electrolyte Homeostasis in the Early Adaptation Period Pubmed:35327814
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPA365Mu01 Recombinant Copeptin (CPP) Positive Control; Immunogen; SDS-PAGE; WB.
CEA365Mu ELISA Kit for Copeptin (CPP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA365Mu Multiplex Assay Kit for Copeptin (CPP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.