Recombinant Thrombin/Antithrombin Complex (TAT)
- Product No.RPA831Hu01
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceProkaryotic expression
- HostE.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted
- Predicted Molecular Mass83.4kDa
- Accurate Molecular Mass83kDa(Analysis of differences refer to the manual)
- Residues & TagsIle364~Glu622+GGGGS*3+His33~Lys464 with N-terminal His Tag
- Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder
- Purity> 80%
- Isoelectric Point7.8
-
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 140
For more details, please contact local distributors! US$ 350 US$ 700 US$ 2100 US$ 5250
SEQUENCE
USAGE
Reconstitute in ddH2O to a concentration of 0.1-0.4 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
- BCA Protein Quantification Kit
- Molecular Mass Marker for Protein
- Monoclonal Antibody Customized Service
- Polyclonal Antibody Customized Service
- Protein Activity Test Experiment Service
- Immunoprecipitation (IP) Experiment Service
- TBST Buffer
- TBS Buffer
- TRIS Buffer
- Spike RBD Protein (S-RBD)
- Protein G
- Protein A
Magazine | Citations |
IUBMB LIFE | Genetic repression of mouse VEGF expression regulates coagulation cascade. PubMed: 21086498 |
Thrombosis Research | Treatment with unfractionated heparin attenuates coagulation and inflammation in endotoxemic mice ScienceDirect: S0049384811004166 |
Journal of Thrombosis and Haemostasis | High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality Wiley: source |
3 | Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling Nature: 20120329 |
Am J Respir Cell Mol Bio | Prolonged Exposure to Sphingosine 1–Phosphate Receptor-1 Agonists Exacerbates Vascular Leak, Fibrosis, and Mortality after Lung Injury PubMed: PMC2993087 |
PLoS One | Host Defense Peptides of Thrombin Modulate Inflammation and Coagulation in Endotoxin-Mediated Shock and Pseudomonas aeruginosa Sepsis PubMed: PMC3521733 |
Haemetology | Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India Pubmed: 23992124 |
Am J Transl Res. | Selected hemostatic parameters in patients with pancreatic tumors. Pubmed:Pmc4297344 |
PLOS ONE | TFPI1 Mediates Resistance to Doxorubicin in Breast Cancer Cells by Inducing a Hypoxic-Like Response Pubmed:24489651 |
Leukemia | Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs) Pubmed:24667943 |
Anesthesia & Analgesia | Thrombomodulin Improved Liver Injury, Coagulopathy, and Mortality in an Experimental Heatstroke Model in Mice Pubmed:24781566 |
Cell Transplantation | Evidence of a Pivotal Role for the Distal Part of the Complement Cascade in the Diurnal Release of Hematopoietic Stem Cells Into Peripheral Blood Pubmed:26087465 |
European Journal of Pharmacology | (S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coaCavia (Guinea pig )lation Pubmed:27343380 |
J Thromb Haemost. | Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis. pubmed:27813324 |
Blood Cells, Inflammation and Infection | Nebulized Heparin Attenuates Pulmonary Coagulopathy and Inflammation through Alveolar Macrophages in a Rat Model of Acute Lung Injury pubmed:29202212 |
SCIENCE TRANSLATIONAL MEDICINE | Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension pubmed:28148841 |
32 | Activated TAFI Promotes the Development of Chronic Thromboembolic Pulmonary Hypertension: A Possible Novel Therapeutic Target pubmed:28289017 |
Thrombosis andHaemostasis | Nebulized anti-coagulants as a therapy for acute lung injury and acute respiratory distress syndrome Pubmed: 29202212 |
Thrombosis Research | The circadian rhythm of selected parameters of the hemostasis system in healthy people |
Experimental Neurobiology | Transduced Tat-aldose Reductase Protects Hippocampal Neuronal Cells against Oxidative Stress-induced Damage Pubmed: 31698553 |
LIVER TRANSPLANTATION | The impact of dabigatran treatment on sinusoidal protection against hepatic ischemia‐reperfusion injury in mice Pubmed: 33108682 |
Am J Physiol Heart Circ Physiol | Doxorubicin contributes to thrombus formation and vascular injury via enhancing platelet functions in vivo Pubmed: 32469636 |
Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … 34169407 |
Intensive Care Med Exp | Complement factor D is linked to platelet activation in human and rodent sepsis 34396466 |