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Recombinant Thrombin/Antithrombin Complex (TAT)

  • Product No.RPA831Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationExtracellular matrix
  • Predicted Molecular Mass83.5kDa
  • Accurate Molecular Mass84kDa(Analysis of differences refer to the manual)
  • Residues & TagsIle361~Gly618+GGGGS*3+His33~Asn465 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 80%
  • Isoelectric Point8.5
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 148  US$ 370  US$ 740  US$ 2220  US$ 5550 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
IUBMB LIFE Genetic repression of mouse VEGF expression regulates coagulation cascade. PubMed: 21086498
Thrombosis Research Treatment with unfractionated heparin attenuates coagulation and inflammation in endotoxemic mice ScienceDirect: S0049384811004166
Journal of Thrombosis and Haemostasis High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality Wiley: source
3 Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling Nature: 20120329
Am J Respir Cell Mol Bio Prolonged Exposure to Sphingosine 1–Phosphate Receptor-1 Agonists Exacerbates Vascular Leak, Fibrosis, and Mortality after Lung Injury PubMed: PMC2993087
PLoS One Host Defense Peptides of Thrombin Modulate Inflammation and Coagulation in Endotoxin-Mediated Shock and Pseudomonas aeruginosa Sepsis PubMed: PMC3521733
Haemetology Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India Pubmed: 23992124
Am J Transl Res. Selected hemostatic parameters in patients with pancreatic tumors. Pubmed:Pmc4297344
PLOS ONE TFPI1 Mediates Resistance to Doxorubicin in Breast Cancer Cells by Inducing a Hypoxic-Like Response Pubmed:24489651
Leukemia Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs) Pubmed:24667943
Anesthesia &amp; Analgesia Thrombomodulin Improved Liver Injury, Coagulopathy, and Mortality in an Experimental Heatstroke Model in Mice Pubmed:24781566
Cell Transplantation Evidence of a Pivotal Role for the Distal Part of the Complement Cascade in the Diurnal Release of Hematopoietic Stem Cells Into Peripheral Blood Pubmed:26087465
European Journal of Pharmacology (S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coaCavia (Guinea pig )lation Pubmed:27343380
J Thromb Haemost. Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis. pubmed:27813324
Blood Cells, Inflammation and Infection Nebulized Heparin Attenuates Pulmonary Coagulopathy and Inflammation through Alveolar Macrophages in a Rat Model of Acute Lung Injury pubmed:29202212
SCIENCE TRANSLATIONAL MEDICINE Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension pubmed:28148841
32 Activated TAFI Promotes the Development of Chronic Thromboembolic Pulmonary Hypertension: A Possible Novel Therapeutic Target pubmed:28289017
Thrombosis andHaemostasis Nebulized anti-coagulants as a therapy for acute lung injury and acute respiratory distress syndrome Pubmed: 29202212
Thrombosis Research The circadian rhythm of selected parameters of the hemostasis system in healthy people
Experimental Neurobiology Transduced Tat-aldose Reductase Protects Hippocampal Neuronal Cells against Oxidative Stress-induced Damage Pubmed: 31698553
LIVER TRANSPLANTATION The impact of dabigatran treatment on sinusoidal protection against hepatic ischemia‐reperfusion injury in mice Pubmed: 33108682
Am J Physiol Heart Circ Physiol Doxorubicin contributes to thrombus formation and vascular injury via enhancing platelet functions in vivo Pubmed: 32469636
Intensive Care Medicine Experimental Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … 34169407
Intensive Care Med Exp Complement factor D is linked to platelet activation in human and rodent sepsis 34396466
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPA831Mu01 Recombinant Thrombin/Antithrombin Complex (TAT) Positive Control; Immunogen; SDS-PAGE; WB.
SEA831Mu ELISA Kit for Thrombin/Antithrombin Complex (TAT) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA831Mu Multiplex Assay Kit for Thrombin/Antithrombin Complex (TAT) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.