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Synthetic Amyloid Beta Peptide 1-42 (Ab1-42)

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Neuropsychopharmacology Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease Pubmed: 23493042
Neuropharmacology and analgesia The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1–42 seeding and short-term memory deficits in the Aβ25–35 mouse model of Alzheimer's disease Pubmed: 23123349
世界科技研究与发展(World Sci-tech R & D) 慢病毒介导的ＣＢＳ基因过表达对原代皮质神经元 Globesci:Source
南方医科大学学报 外源性硫化氢对高糖条件下原代神经元β淀粉样蛋白的影响 J-Smu:Source
Neurochemical research Effects of Aluminium on β-Amyloid (1–42) and Secretases (APP-Cleaving Enzymes) in Rat Brain Pubmed:24792732
Indian J Biochem Biophys. Amyloid ? lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity Pubmed:25296496
Cell Mol Neurobiol Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells PubMed: 25809614
Neuropsychiatr Dis Treat Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex PubMed: 26316755
Neurochem Int Geniposide attenuates insulin-deficiency-induced acceleration of β-amyloidosis in an APP/PS2 transgenic model of Alzheimer's disease PubMed: 25882166
Journal of Alzheimer’s Parkinsonism & Dementia The Potential Effect of Epigallocatechin-3-Gallate alone or in Combination with Vitamin E and Selenium on Alzheimer's Disease Induced by Aluminum in Rats open-access:
世界科技研究与发展 芝麻素对高糖条件下PC12细胞Aβ和BACE-1表达的影响 article:10299
Am J Alzheimers Dis Other Demen. Tong Luo Jiu Nao, a Chinese Medicine Formula, Reduces Inflammatory Stress in a Mouse Model of Alzheimer's Disease Pubmed:26993489
Світ медицини та біології ОСОБЕННОСТИ ПРОЦЕССОВ ФОРМИРОВАНИЯ ПОКАЗАТЕЛЕЙ ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ ВЫСШЕЙ НЕРВНОЙ ДЕЯТЕЛЬНОСТИ И ХАРАКТЕРИСТИКИ ВНИМАНИЯ СТУДЕНТОВ SMB-2016-03-062.pdf
世界科技研究与发展 芝麻素对高糖条件下PC12 细胞Aß 和BACE 1 表达的影响 QK:92621A
Archives of Pharmacal Research Geniposide attenuates the level of Aβ1–42 via enhancing leptin signaling in cellular and APP/PS1 transgenic mice pubmed:28160136
Food Funct. Effects of dietary glucocerebrosides from sea cucumber on the brain sphingolipid profiles of mouse models of Alzheimer's disease. pubmed:28232989
Scientific Reports Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease articles:srep41041.ris
Journal of Medicinal Food Cerebrosides from Sea Cucumber Protect Against Oxidative Stress in SAMP8 Mice and PC12 Cells pubmed:28406733
Journal of Nutritional Biochemistry Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet Pubmed:29986309
Biochemical Pharmacology Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats Pubmed:30028991
Journal of Affective Disorders Sub-chronic celecoxib prevents soluble beta amyloid-induced depressive-like behaviour in rats Pubmed:29879605
Biomedicine & Pharmacotherapy Punicalagin ameliorates the elevation of plasma homocysteine, amyloid-β, TNF-α and apoptosis by advocating antioxidants and modulating apoptotic mediator proteins in brain modulating apoptotic mediator … Pubmed:29579708
Journal of Agricultural and Food Chemistry Effects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer's Disease in APP/PS1 Double-Transgenic Mice Pubmed:29695154
Neurotoxicology Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats Pubmed:29522778
Biochemical and Biophysical Research Communications CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease Pubmed:29777699
Oncotarget Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse … Pubmed:29731975
Experimental and Therapeutic Medicine Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β‑amyloid production and tau hyperphosphorylation Doi: 10.3892/etm.2018.6860
非编码RNA miR-137 调控tau 蛋白磷酸化和L 型钙离子通道CACNA1C 参与阿尔茨海默病的发生
台湾农业研究 (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
The Efficacy of Sauropus androgynus Leaves Extract To Improve Cognitive Function in Wistar Rats Induced Alzheimer's
Neurotoxicity Research Effect of Aluminum-Maltolate on the Content of Aβ Protein and the Expression of ApoER2, VLDLRs, and LRP1 in PC12-ApoE4 Cells Pubmed: 30649678
Neurochemical Research Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation Pubmed: 30756214
Molecular and Cellular Biochemistry Repetitive transcranial magnetic stimulation protects mice against 6-OHDA-induced Parkinson's disease symptoms by regulating brain amyloid β level
PLoS One Obstructive sleep apnea may increase the risk of Alzheimer's disease Pubmed: 31487291
Metabolic Brain Disease Nanoformulated ellagic acid ameliorates pentylenetetrazol-induced experimental epileptic seizures by modulating oxidative stress, inflammatory cytokines and … Pubmed: 31728888
博士论文 Neurobiological determinants of depressive-like symptoms in rodents
Pharmacognosy Magazine Mahanimbine-induced neuroprotection via cholinergic system and attenuated amyloidogenesis as well as neuroinflammation in lipopolysaccharides-induced …
biosciences biotechnology research asia Dietary Malted Barley Grain Improved Structure and Function of Spinal Cord of Mother Rats fed on a high cholesterol diet.
Neurochem Res Ex Vivo Investigation of Bexarotene and Nicotinamide Function as a Protect?ve Agent on Rat Synaptosomes Treated with A¦Â (1-42) 33428094
Food Funct Comparative study on the effects of phosphatidylserine rich in DHA and EPA on A¦Â-intervened Alzheimer's disease using cell models 33876786
Int J Neurosci Protective effects of repetitive transcranial magnetic stimulation against 6-OHDA-induced Parkinson's symptoms in a mice model: the key role of miR-409-3p/PDHB ¡­ 34078216
Brain Res Bul Immunization with A¦Â3-10-KLH vaccine improves cognitive function and ameliorates mitochondrial dysfunction and reduces Alzheimer's disease-like pathology in Tg ¡­ 34044034
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS The effect of a 6-month Ketogenic Medium-Chain Triglyceride Supplement on Plasma Cardiometabolic and Inflammatory Markers in Mild Cognitive?¡­ 33906081
Crystals Potential Therapeutic Effects of New Ruthenium (III) Complex with Quercetin: Characterization, Structure, Gene Regulation, and Antitumor and Anti-Inflammatory Studies (RuIII/Q Novel Complex Is a Potent Immunoprotective Agent)
Neurosci Lett GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal 34695452
Arch Gerontol Geriatr The influence of vinpocetine alone or in combination with Epigallocatechin-3-gallate, Coenzyme COQ10, Vitamin E and Selenium as a potential neuroprotective … 34706318
Metab Brain Dis Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … Pubmed:35312928
Medicinal Chemistry Research New Thienopyridine Scaffold as An Antidementia Lead: In Silico Study and Biological Screening
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
CPA946Hu12 BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
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CPA946Hu11 BSA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu31 KLH Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu22 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
CPA946Hu21 OVA Conjugated Amyloid Beta Peptide 1-42 (Ab1-42) Immunogen; SDS-PAGE; WB.
PAA946Hu08 Polyclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MAA946Hu21 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MAA946Hu22 Monoclonal Antibody to Amyloid Beta Peptide 1-42 (Ab1-42) WB; IHC; ICC; IP.
MEA946Hu Mini Samples ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA946Hu ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA946Hu High Sensitive ELISA Kit for Amyloid Beta Peptide 1-42 (Ab1-42) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA946Hu Multiplex Assay Kit for Amyloid Beta Peptide 1-42 (Ab1-42) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.