Erythropoietin is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow.Also called hematopoietin or hemopoietin, it is produced by the peritubular capillary endothelial cells in the kidney, and is the hormone that regulates red blood cell production.
It also has other known biological functions. For example, erythropoietin plays an important role in the brain's response to neuronal injury.EPO is also involved in the wound healing process.When exogenous EPO is used as a performance-enhancing drug, it is classified as an erythropoiesis-stimulating agent (ESA). Exogenous EPO can often be detected in blood, due to slight difference from the endogenous protein, for example in features of posttranslational modification.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Hu01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA028Hu61 | Eukaryotic Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APA028Hu01 | Active Erythropoietin (EPO) | Cell culture; Activity Assays. | |
APA028Hu61 | Active Erythropoietin (EPO) | Cell culture; Activity Assays. | |
APA028Hu62 | Active Erythropoietin (EPO) | Cell culture; Activity Assays. | |
Antibodies | PAA028Hu01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
MAA028Hu22 | Monoclonal Antibody to Erythropoietin (EPO) | WB,IHC | |
LAA028Hu71 | Biotin-Linked Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC. | |
PAA028Hu06 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
MAA028Hu23 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
MAA028Hu26 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
MAA028Hu21 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
MAA028Hu24 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
MAA028Hu25 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Hu | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA028Hu | CLIA Kit for Erythropoietin (EPO) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Mu01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA028Mu02 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPA028Mu03 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA028Mu01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
PAA028Mu02 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
PAA028Mu03 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Mu | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA028Mu | CLIA Kit for Erythropoietin (EPO) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Ra01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
APA028Ra61 | Active Erythropoietin (EPO) | Cell culture; Activity Assays. | |
EPA028Ra61 | Eukaryotic Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA028Ra01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
MAA028Ra21 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Ra | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA028Ra | CLIA Kit for Erythropoietin (EPO) | Chemiluminescent immunoassay for Antigen Detection. | |
AEA028Ra | ELISA Kit for Anti-Erythropoietin Antibody (Anti-EPO) | Enzyme-linked immunosorbent assay for Antibody Detection. |
Organism species: Rhesus monkey (Simian)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Si01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA028Si01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
MAA028Si21 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Si | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Ca01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA028Ca61 | Eukaryotic Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APA028Ca61 | Active Erythropoietin (EPO) | Cell culture; Activity Assays. | |
Antibodies | PAA028Ca01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
MAA028Ca21 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Ca | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Po01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA028Po01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
MAA028Po21 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Po | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Bo01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Erythropoietin (EPO) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Erythropoietin (EPO) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEA028Bo | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Capra hircus; Caprine (Goat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Cp01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA028Cp01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Erythropoietin (EPO) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Erythropoietin (EPO) | ELISA Kit Customized Service Offer |
Organism species: Ovis aries; Ovine (Sheep)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Ov01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Erythropoietin (EPO) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Erythropoietin (EPO) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Erythropoietin (EPO) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Erythropoietin (EPO) | ELISA Kit Customized Service Offer |
Organism species: Equus caballus; Equine (Horse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA028Eq01 | Recombinant Erythropoietin (EPO) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA028Eq01 | Polyclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. |
MAA028Eq21 | Monoclonal Antibody to Erythropoietin (EPO) | WB; IHC; ICC; IP. | |
Assay Kits | SEA028Eq | ELISA Kit for Erythropoietin (EPO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Isolation and characterization of genomic and cDNA clones of human erythropoietin."Nature 313:806-810(1985) [PubMed] [Europe PMC] [Abstract]
- "Cloning and expression of the human erythropoietin gene."Proc. Natl. Acad. Sci. U.S.A. 82:7580-7584(1985) [PubMed] [Europe PMC] [Abstract]
- "Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes."Genome Res. 8:1060-1073(1998) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Gene expression of mutant erythropoietin in hepatocellular carcinoma."Biochem. Biophys. Res. Commun. 195:717-722(1993) [PubMed] [Europe PMC] [Abstract]
- "Structural characterization of human erythropoietin."J. Biol. Chem. 261:3116-3121(1986) [PubMed] [Europe PMC] [Abstract]
- "Isolation of human erythropoietin with monoclonal antibodies."J. Biol. Chem. 259:2707-2710(1984) [PubMed] [Europe PMC] [Abstract]
- "Comparative study of the asparagine-linked sugar chains of human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells."J. Biol. Chem. 263:3657-3663(1988) [PubMed] [Europe PMC] [Abstract]
- "Site-specific glycosylation of human recombinant erythropoietin: analysis of glycopeptides or peptides at each glycosylation site by fast atom bombardment mass spectrometry."Biochemistry 27:8618-8626(1988) [PubMed] [Europe PMC] [Abstract]
- "Structures and functional roles of the sugar chains of human erythropoietins."Glycobiology 1:337-346(1991) [PubMed] [Europe PMC] [Abstract]
- "Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin."Blood 98:3626-3634(2001) [PubMed] [Europe PMC] [Abstract]
- "Efficiency of signalling through cytokine receptors depends critically on receptor orientation."Nature 395:511-516(1998) [PubMed] [Europe PMC] [Abstract]
- "NMR structure of human erythropoietin and a comparison with its receptor bound conformation."Nat. Struct. Biol. 5:861-866(1998) [PubMed] [Europe PMC] [Abstract]
- "Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications." Proc. Natl. Acad. Sci. U.S.A. 105:6998-7003(2008) [PubMed] [Europe PMC] [Abstract]