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Taxilin Alpha (TXLNa)

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IL14; TXLN; HMW-BCGF; High Molecular Weight B-Cell Growth Factor; Interleukin 14

Taxilin Alpha (TXLNa)
CCC B182
HGNC 30685
MGI 105968
PubMed 21551945
UniProt P40222
Wiki IL14

TXLN interacts with STX3 through its coiled-coil domain.TXLN also interacts with STX1A and STX4. Immunofluorescence and confocal microscopy demonstrated that coexpression of TXLN with STX4 caused relocalization of TXLN from the cytosol to the plasma membrane. Overexpression of TXLN in PC12 cells inhibited human growth hormone exocytosis in response to high potassium levels.  The predicted TXLN protein contains 546 amino acids and has a calculated molecular mass of 62 kD. It has a long C-terminal coiled-coil domain, 24 potential phosphorylation sites, 1 N-glycosylation site, 10 N-myristoylation sites, and 3 EF-hand motifs. Northern blot analysis detected a major 5.1-kb TXLN transcript in all tissues tested, as well as 2.1- and 1.5-kb TXLN transcripts in heart, liver, and pancreas.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB182Hu01 Recombinant Taxilin Alpha (TXLNa) Positive Control; Immunogen; SDS-PAGE; WB.
APB182Hu01 Active Taxilin Alpha (TXLNa) Cell culture; Activity Assays.
Antibodies PAB182Hu01 Polyclonal Antibody to Taxilin Alpha (TXLNa) WB; IHC
MAB182Hu22 Monoclonal Antibody to Taxilin Alpha (TXLNa) WB; IHC; ICC; IP.
Assay Kits SEB182Hu ELISA Kit for Taxilin Alpha (TXLNa) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB182Mu01 Recombinant Taxilin Alpha (TXLNa) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB182Mu01 Polyclonal Antibody to Taxilin Alpha (TXLNa) WB; IHC; ICC; IP.
Assay Kits SEB182Mu ELISA Kit for Taxilin Alpha (TXLNa) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Taxilin Alpha (TXLNa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Taxilin Alpha (TXLNa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taxilin Alpha (TXLNa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taxilin Alpha (TXLNa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Alpha (TXLNa) ELISA Kit Customized Service Offer
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