Epstein Barr Virus Induced Protein 3 (EBI3)
[Edit]IL27B; IL27-B; Interleukin 27B; Epstein-Barr virus-induced gene 3 protein; EBV-induced gene 3 protein
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Epstein-Barr virus induced gene 3was identified by the induction of its expression in B lymphocytes by Epstein-Barr virus infection. The protein encoded by this gene is a secreted glycoprotein, which is a member of the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). It plays a role in regulating cell-mediated immune responses.EBI3 is a subunit in 2 distinct heterodimeric cytokines: interleukin-27 (IL27) and IL35.
IL27 is composed of p28 (IL27) and EBI3. IL27 can trigger signaling in T cells, B cells, and myeloid cells. IL35, an inhibitory cytokine involved in regulatory T-cell function, is composed of EBI3 and the p35 subunit of IL12.Interleukin-27 (IL-27)is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (IL-27B) and IL27-p28 (known as IL-30).
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD206Hu01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAD206Hu01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| MAD206Hu22 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. | |
| LAD206Hu71 | Biotin-Linked Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC. | |
| LAD206Hu81 | FITC-Linked Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| MAD206Hu24 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. | |
| Assay Kits | SCD206Hu | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD206Mu01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPD206Mu02 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAD206Mu01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAD206Mu02 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. | |
| Assay Kits | SED206Mu | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCD206Mu | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | ELISA Kit Customized Service Offer |
- "A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes."J. Virol. 70:1143-1153(1996) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
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- "Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin."Proc. Natl. Acad. Sci. U.S.A. 94:12041-12046(1997) [PubMed] [Europe PMC] [Abstract]
- "IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells." Immunity 16:779-790(2002) [PubMed] [Europe PMC] [Abstract]
- "The biology and therapeutic potential of interleukin 27."J. Mol. Med. 85:661-672(2007) [PubMed] [Europe PMC] [Abstract]