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Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)

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CMD1S; CMH1; MPD1; MYHCB; Myopathy,Distal 1; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform

Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)
CCC D418
HGNC 7577
MGI 2155600
PubMed 12788380
RGD 62030
UniProt P12883
Wiki MYH7
MYH7 is a gene encoding a myosin heavy chain beta (MHC-β) isoform (slow twitch) expressed primarily in the heart.In early fetal development, MHC-β is predominately expressed in the ventricles, while MHC-α is predominantly expressed in the atria. In healthy adult hearts, MHC-α is predominantly expressed in the atria (>90%), while MHC-β (~50%) is expressed in the atria of failing adult hearts. In vitro studies have demonstrated that newly formed cardiac myocytes express MHC-β, and after prolonged (1-5 weeks) contractile activity MHC-α becomes detectable. An allelic variant of this gene is associated with approximately 40% of the cases of Hypertrophic cardiomyopathy (HCM). This condition is an autosomal-dominant disease, in which a single copy of the variant gene causes enlargement of the left ventricle of the heart.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD418Hu01 Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Positive Control; Immunogen; SDS-PAGE; WB.
RPD418Hu02 Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD418Hu01 Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
MAD418Hu21 Monoclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
LAD418Hu81 FITC-Linked Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IF.
PAD418Hu02 Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
MAD418Hu22 Monoclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB
MAD418Hu23 Monoclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
Assay Kits SED418Hu ELISA Kit for Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD418Mu01 Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Positive Control; Immunogen; SDS-PAGE; WB.
RPD418Mu02 Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD418Mu01 Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
PAD418Mu02 Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
Assay Kits SED418Mu ELISA Kit for Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD418Ra01 Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD418Ra01 Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
MAD418Ra21 Monoclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) WB; IHC; ICC; IP.
Assay Kits SED418Ra ELISA Kit for Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7) Enzyme-linked immunosorbent assay for Antigen Detection.
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  35. ErratumHeart 81:330-330(1999)
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  64. Unpublished observations (OCT-2004)
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