Splenic Vascular Endothelial Cells (SVEC)

The spleen is the body's largest immune organ, total systemic lymphoid tissue 25%, containing a large number of lymphocytes and macrophages, cellular and humoral immunity center.

Splenic vascular endothelial cells (SEC), similar to other endothelial cells formed between the blood and subcutaneous tissue natural interface. Previous studies have shown that there is an interesting connection between splenic vascular endothelial cells and splenic hamartoma with capillary hemangioma. Splenic vascular endothelial cells also provide a supportive microenvironment for the development of dendritic cells. In addition, the interaction of endothelial cells in splenic macrophage changes will lead to a rapid destruction of red blood cells. These results suggest that splenic vascular endothelial cells may play a powerful role in the mononuclear phagocyte system.