Conjunctival Epithelial Cells (CEC)

The conjunctiva is a translucent membrane covering the inner surface of the eyelid. It is composed of two layers of epithelial cells. Whether the specific expression of keratin is a marker of difference between corneal epithelial cells and Conjunctival epithelial cells.

Conjunctival epithelial cells（CEC）are covered with a mucin rich polysaccharide protein complex, which promotes tear adhesion, prevents penetration of pathogens, and provides lubrication. Lack or loss of mucin / polysaccharide may cause squamous metaplasia, which may lead to dry eye and ocular surface disease. Conjunctival epithelial cells respond to histamine by stimulating the metabolism and secretion of cytokines. Conjunctival epithelial cells not only have high regeneration ability in vivo, but also show high reproductive activity in vitro. Conjunctival epithelial cells provide a good model for the study of drug toxicity and drug screening in vitro.