Periodontal Ligament Fibroblasts (PDLF)

The periodontal ligament is a group of specialized connective tissue fibers that essentially attach a tooth to the alveolar bone within which it sits.Periodontal ligament fibroblasts（PDLF）are the main interstitial cells in the periodontal connective tissue, which is the main cell of periodontal tissue. It is involved in the process of the lesion, repair and regeneration of periodontal tissue. It has become the main research object in the study of the effects of various physical, chemical and biological factors on periodontal tissues. Factors that induce glutathione synthesis of human PDLF may be used for further chemoprevention of cigarette smoking-related periodontal diseases.The gingival fibroblasts was slightly shorter than that of periodontal ligament fibroblasts, while the proliferation activity of periodontal fibroblasts was higher than that of gingival fibroblasts. Although the two kinds of cells were derived in mesoderm fibroblasts and in morphology and gingival into fiber cells similar to, but periodontal membrane into fiber cells in the maintenance of tissue integrity shows different functional activity.