Adipose Microvascular Endothelial Cells (AMEC)

Microvascular endothelial cells line blood vessels and contribute to many biological processes such as angiogenesis, coagulation, trafficking of lymphocytes, and the inflammatory response. Adipose microvascular endothelial cells (AMEC) are closely related wiht the proliferation of preadipocytes. It has been found that the adipose microvascular endothelial cells growth is stimulated by VEEG secreted by adipocyte.

Co-culture of human adipose MSCs with human adipose MEC will serve as an effective cell pair to induce angiogenesis and vessel-like network formation in three-dimensional scaffolds in vitro.highly complex vessel networks within engineered tissues will improve integration within the host tissue. Moreover, EC-MSC-embedded scaffolds may present an appropriate model for studying angiogenesis under physiologically relevant conditions.