Aorta Adventitial Fibroblasts (AAF)

Aorta adventitial fibroblasts are a type of connective tissue cells that are found in the outer layer of the aorta,Aorta adventitial fibroblasts are cells found in the outermost layer of the aorta, which is the largest artery in the body. These fibroblasts play a role in maintaining the structural integrity of the aorta by producing and organizing the extracellular matrix, which provides support and strength to the blood vessel. They also play a role in regulating inflammation and immune responses in the aorta. Dysfunction of aorta adventitial fibroblasts has been implicated in various cardiovascular diseases, including aortic aneurysm and atherosclerosis. Studying these cells may provide insights into the development of new treatments for these conditions.