The RLE-6TN cell line is a rat lung epithelial cell line that has been widely used in research related to lung biology, respiratory diseases, toxicology, and drug metabolism. These cells were originally isolated from the lungs of male Wistar rats and immortalized by transfection with the SV40 large T antigen.
RLE-6TN cells exhibit characteristics of type II alveolar epithelial cells and express surfactant proteins, making them a valuable model system for studying lung function and surfactant metabolism. Researchers have used RLE-6TN cells to investigate mechanisms of lung injury, inflammation, fibrosis, and cancer, as well as to evaluate the toxicity of various compounds on lung cells.
Overall, the RLE-6TN cell line has been instrumental in advancing our understanding of lung biology and disease processes, and has been a valuable tool for screening potential therapeutics and studying the effects of environmental exposures on the lung.
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Cells | CSI378Ra11 | Rat RLE-6TN Lung Epithelial Cells (RLE-6TN) | RLE-6TN cells are used to investigate mechanisms of lung injury, inflammation, fibrosis, and cancer, as well as to evaluate the toxicity of various compounds on lung cells. |
| Extracts | n/a | Extract of RLE-6TN Lung Epithelial Cells (RLE-6TN) | Total Protein/DNA/RNA Extract Customized Service Offer |
| Mediums | MSI378Ra11 | Medium for Rat RLE-6TN Lung Epithelial Cells (RLE-6TN) | Complete Medium for the culture of RLE-6TN cell line |