A172 Glioblastoma Cells (A172)

A172 cell line is a widely used human glioblastoma cell line that was derived from a tumor in the brain of a 52-year-old male patient. Glioblastoma is the most common and aggressive form of primary brain cancer in adults, and the A172 cell line serves as a valuable model for studying the biology of glioblastoma and testing potential therapeutic strategies.

A172 cell line is characterized by its high proliferative capacity, invasive behavior, and resistance to conventional cancer therapies such as chemotherapy and radiation. These features closely resemble the aggressive nature of glioblastoma tumors in patients, making A172 cells a relevant model for studying the molecular mechanisms of glioblastoma progression and drug resistance.

Researchers use the A172 cell line to investigate various aspects of glioblastoma biology, including cell signaling pathways, gene expression profiles, and responses to different treatments. By studying A172 cells, scientists aim to uncover new insights into the underlying mechanisms of glioblastoma progression and identify novel therapeutic targets for the development of more effective treatments for this devastating disease.