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RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2)

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p150; RAB3-GAP150; RAB3GAP150; Rab3 GTPase-activating protein non-catalytic subunit; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP regulatory subunit

RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2)
CCC M082
HGNC 17168
PubMed 20967465
UniProt Q9H2M9
Wiki RAB3GAP2
Members of the RAB3 protein family are implicated in Ca(2+)-dependent exocytosis. RAB3GAP, which is involved in regulation of RAB3 activity, is a heterodimeric complex consisting a 130-kD catalytic subunit (RAB3GAP1) and a 150-kD noncatalytic subunit (RAB3GAP2). RAB3GAP2 contains 1,393 amino acids. Northern blot analysis detected a 7.5-kb transcript in all human tissues examined. Western blot analysis of subcellular fractionated rat brain detected p150 enriched in the synaptic soluble fraction.p150 did not show GAP activity, and the interaction between p150 and p130 did not alter the activity of p130 or the subcellular distribution of the 2 proteins.RT-PCR ELISA detected highest expression in brain, followed by kidney, ovary, and heart. Intermediate expression was detected in all other tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3 GTPase Activating Protein Subunit 2 (RAB3GAP2) ELISA Kit Customized Service Offer
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