≡

ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A)

[Edit]

VPP2; ATP6A1; ATP6V1A1; Vma1; VA68; V-type proton ATPase catalytic subunit A; V-ATPase 69 kDa; Vacuolar ATPase isoform VA68; Vacuolar proton pump subunit alpha

ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A)
CCC Q183
HGNC 851
MGI 1201780
PubMed 17272665
RGD 1596464
UniProt P38606
Wiki ATP6V1A
ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist.
The deduced 617-amino acid protein has a predicted molecular mass of about 68 kD and shows 99% sequence identity with the bovine brain subunit A. Northern blot analysis revealed ubiquitous expression of a major 4.8-kb band and a minor 3.4-kb band. They also identified a variant, which they designated HO68, encoding a 615-amino acid protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A) ELISA Kit Customized Service Offer
  1. "Identification of two subunit A isoforms of the vacuolar H(+)-ATPase in human osteoclastoma."J. Biol. Chem. 268:7075-7080(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]