Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12)
[Edit]PRAME Family Member 12
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Several tumor-associated antigen families, such as MAGE, GAGE, PRAME and BAGE, are of particular interest in tumor immunology because their expression, with exception of testis and fetal tissues, seems to be restricted to tumor cells.
PRAMEF12 is a 483 amino acid protein containing three LRR (leucine-rich) repeats and is a member of the PRAME family. PRAMEF12 has homology to a melanoma-associated protein, PRAME. PRAME is a melanoma antigen recognized by cytotoxic T cells (CTLs) and is expressed in a variety of cancer cells, including leukemic cells. The PRAME gene is expressed at a high level in a very large fraction of tumors, such as melanomas, non small-cell lung carcinomas, sarcomas, head and neck tumors and renal carcinomas.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Preferentially Expressed Antigen Of Melanoma Family Member 12 (PRAMEF12) | ELISA Kit Customized Service Offer |
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]