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Recombinant Cluster Of Differentiation 40 Ligand (CD40L)

CD154; TRAP; HIGM1; IGM; IMD3; TBAM; T-BAM; TNFSF5; Gp39; TNF Superfamily Member 5; Hyper-IgM Syndrome; TNF-Related Activation Protein; T-Cell B-Cell Activating Molecule

  • Product No.RPA119Bo01
  • Organism SpeciesBos taurus; Bovine (Cattle) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass48.1kDa
  • Accurate Molecular Mass36kDa(Analysis of differences refer to the manual)
  • Residues & TagsMet113~Leu261 (Accession # P51749) with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point7.68
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 204  US$ 510  US$ 1020  US$ 3060  US$ 7650 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Basic Research in Cardiology Secretome of apoptotic peripheral blood cells (APOSEC) attenuates microvascular obstruction in a porcine closed chest reperfused acute myocardial infarction model: role of platelet aggregation and vasodilation PubMed: 22899170
Molecules The Protective Effects of Alisol A 24-Acetate from Alisma canaliculatum on Ovariectomy Induced Bone Loss in Vivo Pubmed:26760992
Journal of Neuroinflammation Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis. pubmed:28114998
BMC Nephrology Renal effects of metallothionein induction by zinc in vitro and in vivo pubmed:28302075
Toxicology and Applied Pharmacology Effects of diisononyl phthalate on osteopenia in intact mice pubmed:28893586
INTERNATIONAL JOURNAL OF CARDIOLOGY Short and long-term changes in platelet and inflammatory biomarkers after cryoballoon and radiofrequency ablation Pubmed: 30857843
Available at SSRN 3335365  Evaluating the Platelet Activation Related to the Degradation of Biomaterials by Scheme of Molecular Markers
Data in Brief Data for short and long-term prothrombotic biomarkers after cryoballoon and radiofrequency ablation
journal of thoracic and cardiovascular surgery Evaluating Platelet Activation Related to the Degradation of Biomaterials Using Molecular Markers Pubmed: 32812629
Thrombosis Research Feasibility study of use of rabbit blood to evaluate platelet activation by medical devices Pubmed: 31838449
Cancers Predictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control Study Pubmed: 32085544
Persistently higher serum sCD40L levels are associated with mortality in septic patients
Journal of Orthopaedic Translation Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-¦ÊB and MAPK activation 33981577
Bioactive Materials Secretions from hypochlorous acid-treated tumor cells delivered in a melittin hydrogel potentiate cancer immunotherapy 34820587
Catalog No. Related products for research use of Bos taurus; Bovine (Cattle) Organism species Applications (RESEARCH USE ONLY!)
RPA119Bo01 Recombinant Cluster Of Differentiation 40 Ligand (CD40L) Positive Control; Immunogen; SDS-PAGE; WB.
PAA119Bo01 Polyclonal Antibody to Cluster Of Differentiation 40 Ligand (CD40L) WB; IHC; ICC; IP.
LAA119Bo81 FITC-Linked Polyclonal Antibody to Cluster Of Differentiation 40 Ligand (CD40L) WB; IHC; ICC; IF.
LAA119Bo71 Biotin-Linked Polyclonal Antibody to Cluster Of Differentiation 40 Ligand (CD40L) WB; IHC; ICC.