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Recombinant Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)

SFD; TIMP Metallopeptidase Inhibitor 3; Metallopeptidase Inhibitor 3; Sorsby Fundus Dystrophy; Pseudoinflammatory

  • Product No.RPA129Bo01
  • Organism SpeciesBos taurus; Bovine (Cattle) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Extracellular matrix
  • Predicted Molecular Mass24.5kDa
  • Accurate Molecular Mass25kDa(Analysis of differences refer to the manual)
  • Residues & TagsPro31~Thr209 with N-terminal His Tag
  • Buffer Formulation100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point9.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 207  US$ 518  US$ 1036  US$ 3108  US$ 7770 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neuroimmunomodulation Upregulated Expression of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinases in BALB/c Mouse Brain Challenged with Japanese Encephalitis Virus Pubmed: source
Experimental Biology and Medicine Acidic pH conditions mimicking degenerative intervertebral discs impair the survival and biological behavior of human adipose-derived mesenchymal stem cells Rsmjournals: Source
PLoS ONE A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches Plosone: Source
Physiol. Res. The unwounded skin remodeling in animal models of diabetes types 1 and 2. Pubmed: 24020818
VirusDisease Circulating levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases during Japanese encephalitis virus infection Pubmed:26925446
Acta Pharmacol Sin. Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells. pubmed:27890915
Biochemical genetics Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer pubmed:28421310
International Journal of Cancer Circulating and tissue IMP3 levels are correlated with poor survival in renal cell carcinoma Pubmed: 30650187
J. Pers. Med Altered TIMP-3 Levels in the Cerebrospinal Fluid and Plasma of Patients with Alzheimer's Disease Pubmed:35629249
Catalog No. Related products for research use of Bos taurus; Bovine (Cattle) Organism species Applications (RESEARCH USE ONLY!)
RPA129Bo02 Recombinant Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Positive Control; Immunogen; SDS-PAGE; WB.
APA129Bo02 Active Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Cell culture; Activity Assays.
RPA129Bo01 Recombinant Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Positive Control; Immunogen; SDS-PAGE; WB.
PAA129Bo01 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) WB; IHC; ICC; IP.
PAA129Bo02 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) WB; IHC; ICC; IP.
MAA129Bo21 Monoclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) WB; IHC; ICC; IP.
SEA129Bo ELISA Kit for Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA129Bo CLIA Kit for Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Chemiluminescent immunoassay for Antigen Detection.
LMA129Bo Multiplex Assay Kit for Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.