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Recombinant Brain Natriuretic Peptide (BNP)

GC-B; B-Type Natriuretic Peptide; Ventricular Natriuretic Peptide; Gamma-brain natriuretic peptide; Brain natriuretic peptide 32

  • Product No.RPA541Ca01
  • Organism SpeciesCanis familiaris; Canine (Dog) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular Locationn/a
  • Predicted Molecular Massn/a
  • Accurate Molecular Massn/a(Analysis of differences refer to the manual)
  • Residues & TagsN-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point6.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • Downloadn/a
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 240  US$ 600  US$ 1200  US$ 3600  US$ 9000 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in PBS or others.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Heart and Circulatory Physiology B-type natriuretic peptide, vascular endothelial growth factor, endothelin-1, and nitric oxide synthase in chronic mountain sickness APS: source
PLoS One Renalase deficiency in heart failure model of rats_a potential mechanism underlying circulating norepinephrine accumulation. PubMed: 21297953
International Journal of Toxicology Cardiac Troponin T and NT-proBNP as Biomarkers of Early Myocardial Damage in Amitriptyline-Induced Cardiovascular Toxicity in Rats Pubmed: 24055824
JACC ELEVATED ST2 SERUM LEVELS A BIOMARKER FOR CARDIOMYOPATHY IN DUCHENNE MUSCULAR DYSTROPHY Onlinejacc:Source
J Urol.? Why does Adenotonsillectomy Not Correct Enuresis in All Children with Sleep Disordered Breathing? Pubmed:24679871
Life Sci Cardioprotective effects of baicalein on heart failure via modulation of Ca2 PubMed: 26706290
Vlaams Diergeneeskundig Tijdschrift Equine BNP measurement using a porcine BNP enzyme-linked immunoassay: a pilot study Publication: 5950761
Physiological Research Renal Sympathetic Denervation Improves Cardiac Dysfunction PubMed: 25804096
Life Sci Cardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitro Pubmed:26706290
J Ethnopharmacol Danhong injection attenuates isoproterenol-induced cardiac hypertrophy by reCavia (Guinea pig )lating p38 and NF-κb pathway Pubmed:26970569
Echocardiography. Improvement in the prediction of exercise-induced elevation of left ventricular filling pressure in patients with normal left ventricular ejection fraction. pubmed:27779336
SpringerPlus The effect of long-term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic … pubmed:27652141
Heart Lung Circ. Efficacy and Safety of Renal Sympathetic Denervation on Dogs with Pressure Overload-Induced Heart Failure. pubmed:27555054
Clinica Chimica Acta  Plasma concentration of fibronectin is decreased in patients with hypertrophic cardiomyopathy pubmed:27693530
Scientific Reports Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP. pubmed:28091624
Molecular Medicine Report Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure pubmed:28627670
PLoS One Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy pubmed:29240788
Acta Physiologica Beneficial Effects of Renal Denervation on Cardiac Angiogenesis in Rats with Prolonged Pressure Overload pubmed:27575955
International Immunopharmacology Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK pubmed:28410530
Drug Delivery Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy. pubmed:29063791
Science of the Total Environment Co-exposure of silica nanoparticles and methylmercury induced cardiac toxicity and Pubmed:29727991
Scientific Reports An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease Pubmed:29895976
International Journal of Cardiology Cardioprotective effect of substance P in a porcine model of acute myocardial infarction Pubmed:29884290
International Journal of Cardiology High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure Pubmed:30072155
Evidence-based Complementary and Alternative Medicine  Acute Biochemical, Cardiovascular, and Autonomic Response to Hyperbaric (4 atm) Exposure in Healthy Subjects Pubmed:29977313
Molecular Medicine Reports  Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats Pubmed:29956781
Pediatric Cardiology Determinants of Increased Aortic Diameters in Young Normotensive Patients With Turner Syndrome Without Structural Heart Disease Pubmed:29392348
BMC Pharmacology and Toxicology Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis Pubmed:29321061
中国病理生理杂志 和肽素水平对大鼠心肾综合征的早期预测价值 filename:ZBLS201802013
FASEB Journal Signature-oriented investigation of the efficacy of multicomponent drugs against heart failure Pubmed: 30230922
Toxicology Mechanisms and Methods Long-term exposure to crotonaldehyde causes heart and kidney dysfunction through induction of inflammatory and oxidative damage in male Wistar rats Pubmed: 30426860
Van Veterinary Journal Van Veterinary Journal
Kidney International Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome Pubmed: 30770217
Journal of Cellular Physiology Inflammatory cytokines associated with cancer growth induce mitochondria and cytoskeleton alterations in cardiomyocytes Pubmed: 30982981
Cardiology Circulating Connective Tissue Growth Factor Is Associated with Diastolic Dysfunction in Patients with Diastolic Heart Failure Pubmed: 31466059
BIOMEDICINE & PHARMACOTHERAPY Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor Pubmed: 32570118
biochimica et biophysica acta-molecular basis of disease Empagliflozin improves left ventricular diastolic function of db/db mice Pubmed: 32353614
Dapagliflozin: a Sodium-glucose Cotransporter 2 Inhibitor, Attenuates Angiotensin II-induced Cardiac Fibrotic Remodeling by Regulating TGF¦Â1/Smad ¡­ 34116674
Radiation-induced heart energy metabolism dysfunction leads to heart fibrosis
Oxid Med Cell Longev κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca2+-SERCA2a 34373768
Mol Med Rep Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues 34633055
viruses Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model 34452454
Peptides Osteocrin alleviates cardiac hypertrophy via attenuating oxidative stress Pubmed:35218795
Catalog No. Related products for research use of Canis familiaris; Canine (Dog) Organism species Applications (RESEARCH USE ONLY!)
RPA541Ca01 Recombinant Brain Natriuretic Peptide (BNP) Positive Control; Immunogen; SDS-PAGE; WB.
PAA541Ca01 Polyclonal Antibody to Brain Natriuretic Peptide (BNP) WB; IHC; ICC; IP.
LAA541Ca71 Biotin-Linked Polyclonal Antibody to Brain Natriuretic Peptide (BNP) WB; IHC; ICC.
MAA541Ca21 Monoclonal Antibody to Brain Natriuretic Peptide (BNP) WB; IHC; ICC; IP.
CEA541Ca ELISA Kit for Brain Natriuretic Peptide (BNP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA541Ca Multiplex Assay Kit for Brain Natriuretic Peptide (BNP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.