Brain Natriuretic Peptide (BNP)
[Edit]GC-B; B-Type Natriuretic Peptide; Ventricular Natriuretic Peptide; Gamma-brain natriuretic peptide; Brain natriuretic peptide 32
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Brain natriuretic peptide is 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). BNP is named as such because it was originally identified in extracts of porcine brain, although in humans it is produced mainly in the cardiac ventricles.
BNP is co-secreted along with a 76 amino acid N-terminal fragment (NT-proBNP) which is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA541Ra01 | Recombinant Brain Natriuretic Peptide (BNP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA541Ra01 | Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. |
| MAA541Ra21 | Monoclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. | |
| MAA541Ra22 | Monoclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA541Ra | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEA541Ra | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rhesus monkey (Simian)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Complete Antigen of Brain Natriuretic Peptide (BNP) | Antigenic Transformation Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Brain Natriuretic Peptide (BNP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | CEA541Si | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA541Ca01 | Recombinant Brain Natriuretic Peptide (BNP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA541Ca01 | Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. |
| LAA541Ca71 | Biotin-Linked Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC. | |
| MAA541Ca21 | Monoclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA541Ca | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA541Po01 | Recombinant Brain Natriuretic Peptide (BNP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA541Po01 | Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. |
| LAA541Po81 | FITC-Linked Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IF. | |
| LAA541Po71 | Biotin-Linked Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC. | |
| MAA541Po21 | Monoclonal Antibody to Brain Natriuretic Peptide (BNP) | WB; IHC; ICC; IP. | |
| Assay Kits | CEA541Po | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEA541Po | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Complete Antigen of Brain Natriuretic Peptide (BNP) | Antigenic Transformation Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Brain Natriuretic Peptide (BNP) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Brain Natriuretic Peptide (BNP) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | CEA541Ga | ELISA Kit for Brain Natriuretic Peptide (BNP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "The precursor to B-type natriuretic peptide is an O-linked glycoprotein."Arch. Biochem. Biophys. 451:160-166(2006) [PubMed] [Europe PMC] [Abstract]
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- "Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-alpha."FEBS J. 278:1316-1332(2011) [PubMed] [Europe PMC] [Abstract]
- "Structural determinants of natriuretic peptide receptor specificity and degeneracy."J. Mol. Biol. 361:698-714(2006) [PubMed] [Europe PMC] [Abstract]