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Figure. SDS-PAGE
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Instruction Manual
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Recombinant Brain Natriuretic Peptide (BNP)
GC-B; B-Type Natriuretic Peptide; Ventricular Natriuretic Peptide; Gamma-brain natriuretic peptide; Brain natriuretic peptide 32
- Product No.RPA541Hu01
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceProkaryotic expression
- HostE.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted
- Predicted Molecular Mass17.2kDa
- Accurate Molecular Mass19kDa(Analysis of differences refer to the manual)
- Residues & TagsSer103~His134 with Two N-terminal Tags, His-tag and SUMO-tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder
- Purity> 90%
- Isoelectric Point11.0
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Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 192
US$ 480
US$ 960
US$ 2880
US$ 7200
For more details, please contact local distributors!
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
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BCA Protein Quantification Kit
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Molecular Mass Marker for Protein
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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TBST Buffer
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TBS Buffer
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TRIS Buffer
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
| Magazine | Citations |
| Heart and Circulatory Physiology | B-type natriuretic peptide, vascular endothelial growth factor, endothelin-1, and nitric oxide synthase in chronic mountain sickness APS: source |
| PLoS One | Renalase deficiency in heart failure model of rats_a potential mechanism underlying circulating norepinephrine accumulation. PubMed: 21297953 |
| International Journal of Toxicology | Cardiac Troponin T and NT-proBNP as Biomarkers of Early Myocardial Damage in Amitriptyline-Induced Cardiovascular Toxicity in Rats Pubmed: 24055824 |
| JACC | ELEVATED ST2 SERUM LEVELS A BIOMARKER FOR CARDIOMYOPATHY IN DUCHENNE MUSCULAR DYSTROPHY Onlinejacc:Source |
| J Urol.? | Why does Adenotonsillectomy Not Correct Enuresis in All Children with Sleep Disordered Breathing? Pubmed:24679871 |
| Life Sci | Cardioprotective effects of baicalein on heart failure via modulation of Ca2 PubMed: 26706290 |
| Vlaams Diergeneeskundig Tijdschrift | Equine BNP measurement using a porcine BNP enzyme-linked immunoassay: a pilot study Publication: 5950761 |
| Physiological Research | Renal Sympathetic Denervation Improves Cardiac Dysfunction PubMed: 25804096 |
| Life Sci | Cardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitro Pubmed:26706290 |
| J Ethnopharmacol | Danhong injection attenuates isoproterenol-induced cardiac hypertrophy by reCavia (Guinea pig )lating p38 and NF-κb pathway Pubmed:26970569 |
| Echocardiography. | Improvement in the prediction of exercise-induced elevation of left ventricular filling pressure in patients with normal left ventricular ejection fraction. pubmed:27779336 |
| SpringerPlus | The effect of long-term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic … pubmed:27652141 |
| Heart Lung Circ. | Efficacy and Safety of Renal Sympathetic Denervation on Dogs with Pressure Overload-Induced Heart Failure. pubmed:27555054 |
| Clinica Chimica Acta | Plasma concentration of fibronectin is decreased in patients with hypertrophic cardiomyopathy pubmed:27693530 |
| Scientific Reports | Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP. pubmed:28091624 |
| Molecular Medicine Report | Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failure pubmed:28627670 |
| PLoS One | Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy pubmed:29240788 |
| Acta Physiologica | Beneficial Effects of Renal Denervation on Cardiac Angiogenesis in Rats with Prolonged Pressure Overload pubmed:27575955 |
| International Immunopharmacology | Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK pubmed:28410530 |
| Drug Delivery | Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy. pubmed:29063791 |
| Science of the Total Environment | Co-exposure of silica nanoparticles and methylmercury induced cardiac toxicity and Pubmed:29727991 |
| Scientific Reports | An essential role for Wnt/β-catenin signaling in mediating hypertensive heart disease Pubmed:29895976 |
| International Journal of Cardiology | Cardioprotective effect of substance P in a porcine model of acute myocardial infarction Pubmed:29884290 |
| International Journal of Cardiology | High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure Pubmed:30072155 |
| Evidence-based Complementary and Alternative Medicine | Acute Biochemical, Cardiovascular, and Autonomic Response to Hyperbaric (4 atm) Exposure in Healthy Subjects Pubmed:29977313 |
| Molecular Medicine Reports | Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats Pubmed:29956781 |
| Pediatric Cardiology | Determinants of Increased Aortic Diameters in Young Normotensive Patients With Turner Syndrome Without Structural Heart Disease Pubmed:29392348 |
| BMC Pharmacology and Toxicology | Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis Pubmed:29321061 |
| 中国病理生理杂志 | 和肽素水平对大鼠心肾综合征的早期预测价值 filename:ZBLS201802013 |
| FASEB Journal | Signature-oriented investigation of the efficacy of multicomponent drugs against heart failure Pubmed: 30230922 |
| Toxicology Mechanisms and Methods | Long-term exposure to crotonaldehyde causes heart and kidney dysfunction through induction of inflammatory and oxidative damage in male Wistar rats Pubmed: 30426860 |
| Van Veterinary Journal | Van Veterinary Journal |
| Kidney International | Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome Pubmed: 30770217 |
| Journal of Cellular Physiology | Inflammatory cytokines associated with cancer growth induce mitochondria and cytoskeleton alterations in cardiomyocytes Pubmed: 30982981 |
| Cardiology | Circulating Connective Tissue Growth Factor Is Associated with Diastolic Dysfunction in Patients with Diastolic Heart Failure Pubmed: 31466059 |
| BIOMEDICINE & PHARMACOTHERAPY | Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor Pubmed: 32570118 |
| biochimica et biophysica acta-molecular basis of disease | Empagliflozin improves left ventricular diastolic function of db/db mice Pubmed: 32353614 |
| Dapagliflozin: a Sodium-glucose Cotransporter 2 Inhibitor, Attenuates Angiotensin II-induced Cardiac Fibrotic Remodeling by Regulating TGF¦Â1/Smad ¡ 34116674 | |
| Radiation-induced heart energy metabolism dysfunction leads to heart fibrosis | |
| Oxid Med Cell Longev | κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca2+-SERCA2a 34373768 |
| Mol Med Rep | Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues 34633055 |
| viruses | Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model 34452454 |
| Peptides | Osteocrin alleviates cardiac hypertrophy via attenuating oxidative stress Pubmed:35218795 |