Recombinant Cyclin D1 (CCND1)
CCN-D1; BCL1; PRAD1; U21B31; G1/S-Specific Cyclin-D1; Parathyroid Adenomatosis 1; B-Cell CLL/Lymphoma 1; G1/S-Specific Cyclin D1; PRAD1 oncogene
- Product No.RPA585Hu01
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceProkaryotic expression
- HostE.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane, Nucleus, Cytoplasm
- Predicted Molecular Mass63.7kDa
- Accurate Molecular Mass63kDa(Analysis of differences refer to the manual)
- Residues & TagsMet1~Ile295 with N-terminal His and GST Tag
- Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
- Traits Freeze-dried powder
- Purity> 90%
- Isoelectric Point5.6
-
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 140
For more details, please contact local distributors! US$ 350 US$ 700 US$ 2100 US$ 5250
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
- Endotoxin Removal Kit
- BCA Protein Quantification Kit
- Protein Labeling Customized Service
- Molecular Mass Marker for Protein
- Recombinant Protein Customized Service
- Monoclonal Antibody Customized Service
- Polyclonal Antibody Customized Service
- Protein Activity Test Experiment Service
- Immunoprecipitation (IP) Experiment Service
- Buffer
- Endotoxin Removal Kit II
- Real Time PCR Experimental Service
- Spike RBD Protein (S-RBD)
- Protein G
- Protein A
Magazine | Citations |
Biochemical Pharmacology | Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells ScienceDirect: S0006295211002097 |
Leukemia & Lymphoma | The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-62 human leukemia cells Pubmed: 24138332 |
The Journal of Clinical Endocrinology and Metabolism | Antiproliferative and proapoptotic activity of sunitinib on endothelial and anaplastic thyroid cancer cells via inhibition of Akt and ERK1/2 phosphorylation and by down-regulation of cyclin-D1. Pubmed: 23969186 |
Nutrition and Cancer | Common Food Additive Carrageenan Stimulates Wnt/ β-Catenin Signaling in Colonic Epithelium by Inhibition of Nucleoredoxin Reduction Pubmed:24328990 |
The International Journal of Biochemistry & Cell Biology | MicroRNA-149 is epigenetically silenced tumor-suppressive microRNA, involved in cell proliferation and downregulation of AKT1 and cyclin D1 in human … pubmed:27783537 |
Scientific Reports | Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA. pubmed:28533512 |
Investigational new drugs | Development of a dietary formulation of the SHetA2 chemoprevention drug for mice. pubmed:29273857 |
Biochemical Pharmacology | Metronomic vinorelbine is directly active on Non Small Cell Lung Cancer cells and sensitizes the EGFRL858R/T790M cells to reversible EGFR tyrosine kinase … Pubmed:29660315 |
Apoptosis | Licarin A induces cell death by activation of autophagy and apoptosis in non-small cell lung cancer cells Pubmed:29468481 |
Oncology Reports | Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo Pubmed:29517106 |
Oncology Reports | Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo Pubmed:29517103 |
Scientific Reports | Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA Pubmed: 28533512 |
Middle East Journal of Rehabilitation and Health | Antiapoptotic Effects of Continuous Training and Selenium Consumption on the Liver Tissue of Cadmium-Exposed Rats Pubmed: 10.5812/mejrh.91278 |
European journal of medicinal chemistry | Synthesis of novel S-linked dihydroartemisinin derivatives and evaluation of their anticancer activity Pubmed: 31216504 |
Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
RPA585Hu01 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA585Hu02 | Recombinant Cyclin D1 (CCND1) | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA585Hu01 | Polyclonal Antibody to Cyclin D1 (CCND1) | WB |
MAA585Hu22 | Monoclonal Antibody to Cyclin D1 (CCND1) | WB; IHC; ICC; IP. |
SEA585Hu | ELISA Kit for Cyclin D1 (CCND1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA585Hu | Multiplex Assay Kit for Cyclin D1 (CCND1) ,etc. by FLIA (Flow Luminescence Immunoassay) | FLIA Kit for Antigen Detection. |
KSA585Hu01 | ELISA Kit DIY Materials for Cyclin D1 (CCND1) | Main materials for "Do It (ELISA Kit) Yourself". |