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Recombinant Myeloperoxidase (MPO)

  • Product No.RPA601Hu02
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationLysosome
  • Predicted Molecular Mass82.7kDa
  • Accurate Molecular Mass84kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla49~Ser745 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 80%
  • Isoelectric Point9.0
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 121  US$ 303  US$ 606  US$ 1818  US$ 4545 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
International Journal of Medical Sciences Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats PubMed: 21234269
Respiration Protective Effect of Nicotine on Lipopolysaccharide-Induced Acute Lung Injury in Mice Karger: 000319151
Inflammation Preventive Effects of Valnemulin on Lipopolysaccharide-Induced Acute Lung Injury in Mice SpringerLink: 741437t67767777x
Advanced Materials Research A New Immunosensor for Serum Myeloperoxidase Based on Self-Assembly of Multi-Walled Carbon Nanotubes/Thionine/Gold Nanoparticles-Chitosan Scientific:1207
9 T cells that target carcinoembryonic antigen eradicate orthotopic pancreatic carcinomas without inducing autoimmune colitis in mice PubMed: 22750462
European Surgical Research Rosuvastatin Reloading before Cardiac Surgery with Cardiopulmonary Bypass PubMed: 23406839
Toxicology and Industrial Health Protective effects of Ankaferd blood stopper on aspirin-induced oxidative mucosal damage in a rat model of gastric injury. PubMed: 23114375
Experimental Lung Research Protective effect of pravastatin on lipopolysaccharide-induced acute lung injury during neutropenia recovery in mice Pubmed: 23368428
International Immunopharmacology Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis Pubmed: 24126114
Human & experimental toxicology Neuroprotective effects of α-ketoglutarate and ethyl pyruvate against motor dysfunction and oxidative changes caused by repeated 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine exposure in mice Pubmed: 23821591
International Immunopharmacology Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits ScienceDirect: S1567576913004153
PLOS ONE Novel CoQ10 Antidiabetic Mechanisms Underlie Its Positive Effect: Modulation of Insulin and Adiponectine Receptors, Tyrosine Kinase, PI3K, Glucose Transporters, sRAGE and Visfatin in Insulin Resistant/Diabetic Rats Pubmed:24586567
Acta Anaesthesiol Scand. Heparin-binding protein (HBP/CAP37) - a link to endothelin-1 in endotoxemia-induced pulmonary oedema? Pubmed:24611481
Journal of Environmental Pathology, Toxicology and Oncology Protective Effect of?Acacia ferruginea?against Ulcerative Colitis via Modulating Inflammatory Mediators, Cytokine Profile and NF-κB Signal Transduction Pathways Pubmed:24941292
European Journal of Pharmacology Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in rats Pubmed:25084223
Iran J Pharm Res. Comparison of the Effects of Enoxaparin and Heparin on Inflammatory Biomarkers in Patients with ST-segment Elevated Myocardial Infarction: A prospective Open Label Pilot Clinical Trial Pubmed:25237354
Chem Biol Interact.? Gastroprotective effect of nymphayol isolated from Nymphaea stellata (Willd.) flowers: Contribution of antioxidant, anti-inflammatory and anti-apoptotic activities Pubmed:25289771
Journal of Surgical Research Melatonin attenuates intestinal ischemia–reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2 Pubmed:25491174
Neurochemistry International Sulfiredoxin-1 protects primary cultured astrocytes from ischemia-induced damage Pubmed:25620665
Ann N Y Acad Sci.? Modulating effect of Biophytum sensitivum extract on rats with acetic acid-induced ulcerative colitis Pubmed:5243883
J Crohns The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis PubMed: 26116555
Monoclon Antib Immunodiagn Immunother Preparation of Monoclonal Antibodies and a Simple Myeloperoxidase-Immunosorbent Assay for Detecting Human Myeloperoxidase Pubmed:26978734
Clinics and Research in Hepatology and Gastroenterology The efficacy of tyrosine kinase inhibitor dasatinib on colonic mucosal damage in murine model of colitis Pubmed:26823039
Asian J Pharm Clin Res THE ANTI-HYPERCHOLESTEROLEMIC EFFECT OF ULVAN POLYSACCHARIDE EXTRACTED FROM THE GREEN ALGA ULVAFASCIATA ON AGED HYPERCHOLESTEROLEMIC RATS journals:10835
Hepatology. Toll-like receptor 5 signaling restrains T-cell/natural killer T-cell activation and protects against concanavalin A-induced hepatic injury. pubmed:28273362
International Journal of Sports Physiology and Performance  Exploring the Potential of cfDNA Measurements After an Exhaustive Cycle Ergometer Test as a Marker for Performance Related Parameters pubmed:27617485
Journal of Pharmacy and Pharmaceutical Sciences Ellagic Acid Protects Against LPS-Induced Acute Lung Injury Through Inhibition of Nuclear Factor Kappa B, Proinflammatory Cytokines and Enhancement of Interleukin-10 c30adb97b06eb4f27063208df7acb7311368.pdf
Future Microbiology Transplantation of a bacterial consortium ameliorates trinitrobenzenesulfonic acid-induced colitisand intestinal dysbiosis in rats. pubmed:27415182
The Annals of Thoracic Surgery Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model. pubmed:28190546
Biological Rhythm Research Fluctuation in the number, type and activity of blood neutrophils in cows exhibiting successful and unsuccessful completion of gestation cycle 09291016.2017.1311984
Journal of Cancer Research and Treatment Effect of Indole-3-carbinol and/or Metformin on Female Patients with Ulcerative Colitis (Premalignant Condition): Role of Oxidative Stress, Apoptosis and Proinflammatory Cytokines jcrt:5
Identification of Tengfu Jiangya Tablet Target Biomarkers journals:ecam
Hepatology. Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis. pubmed:27775820
LAB ON A CHIP Enzyme catalysis-electrophoresis titration for multiplex enzymatic assay via moving reactionboundary chip. pubmed:27464600
Indian Journal of Animal Research Effect of Poly-herbal mixture and butyric acid feeding on immune parameters of postpartum Murrah buffaloes publication:299575009
The American Journal of Cardiology Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate During Acute Myocardial Infarction and Their Relation to Inflammation and Myocardial Injury pubmed:28867129
Evidence-Based Complementary and Alternative Medicine Identification of Tengfu Jiangya Tablet Target Biomarkers with Quantitative Proteomic Technique pubmed:28408942
Lasers in Medical Science Effect of photobiomodulation therapy on reducingthe chemo-induced oral mucositis severity and on salivary levels of CXCL8/interleuki8, nitrite, and myeloperoxidase in patients undergoing hematopoietic stem cell transplantation: a randomized clinical trial article:10.1007
Experiental And Therapeutic Medicine Plasma proteins as potential targets of abnormal Savda syndrome in asthma patients treated with unique Uighur prescription pubmed:28672924
Frontiers in Immunology Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells 10.3389:fimmu.2017.00824
Journal of Pediatric Surgery Does penile tourniquet application alter bacterial adhesion to rat urethral cells: an in vitro study pubmed:28693848
Food and Agricultural Immunology Ellagic acid protects against LPS-induced acute lung injury through inhibition of nuclear factor kappa B, proinflammatory cytokines and enhancement of interleukin-10 10.1080/09540105.2017.1339670
Oxidative Medicine and Cellular Longevity Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophils pubmed:29081886
Advanced Science Letters Serum Myeloperoxidase in Stable Coronary Artery Disease 10.1166/asl.2017.8512
Tropical Journal of Pharmaceutical Research Hepatoprotective effect of taurine and coenzyme Q10 and their combination against acrylamide-induced oxidative stress in rats 10.4314/tjpr.v16i8.14
deposit once Role of NOD2 and S100A8/S100A9 in the pathogenesis of Coxsackievirus B3-induced myocarditis 10.14279/depositonce-5934
Archives of Medical Research Effects of Sulphasalazine in Cerebral Ischemia Reperfusion Injury in Rat. pubmed:28923326
Frontiers in Immunology The Plasma Kallikrein–Kininogen Pathway is critical in the Pathogenesis of colitis in Mice Pubmed:29467753
Frontiers in Pharmacology Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal … Pubmed:29375374
Biomedicine & Pharmacotherapy Evaluation of the anti-hypertensive effect of Tengfu Jiangya tablet by combination of UPLC-Q-exactive-MS-based metabolomics and iTRAQ-based proteomics … Pubmed:29453042
Molecular Vision Resolvin D1 promotes corneal epithelial wound healing and restoration of mechanical sensation in diabetic mice Pubmed:29643724
Theriogenology Effect of tropical thermal stress on peri-implantation immune responses in cows Pubmed:29625402
Molecular Medicine Reports  Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats Pubmed:29956781
Oncology Letters Hydrogen‑rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus‑activated kinase 2/signal transducer and activator of … Pubmed:29928398
Journal of Veterinary Science Associations of periparturient plasma biochemical parameters, endometrial leukocyte esterase and myeloperoxidase, and bacterial detection with clinical and … Pubmed:29332864
Life Sciences Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent manner Pubmed: 30195035
International Journal of Clinical and Experimental Medicine Effect of β-glucan on acetic acid-induced colitis in rats
BioMed Research International Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway
Beneficial Microbes Bacillus licheniformis Zhengchangsheng® attenuates DSS-induced colitis and modulates the gut microbiota in mice
General Medicine: Open Access Do Late Phase Hyperbaric and Normobaric Oxygen Therapies have Effect on Liver Damage?: An Experimental Sepsis Model
journal of surgical research Posttreatment With LYRM03 Protects Rats From Acute Lung Inflammation Induced by Lipopolysaccharide via Suppressing the NF-κB/MyD88/TLR4 Axis Pubmed: 31255931
Toxicol Ind Health Efficacy assessment of co-treated alpha-ketoglutarate and N-acetyl cysteine against the subchronic toxicity of cyanide in rats Pubmed: 31244408
Journal of Pediatric Surgery The effects of hydrogen-rich saline solution on intestinal anastomosis performed after intestinal ischemia reperfusion injury
Biochemical and Biophysical Research Communications Annexin A1 mimetic peptide Ac2-26 attenuates mechanical injury induced corneal scarring and inflammation Pubmed: 31519322
Cell Proliferation SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection Pubmed: 31782850
Advances in Clinical and Experimental Medicine Effects of ozone preconditioning on recovery of rat colon anastomosis after preoperative radiotherapy Pubmed: 31895975
Brain Research Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats Pubmed: 31926128
ARTHRITIS RESEARCH & THERAPY Native myeloperoxidase is required to make the experimental vasculitis model Pubmed: 31864385
ANALYTICAL CHEMISTRY Rational Modulation of the Luminescence of Upconversion Nanomaterials with Phycocyanin for the Sensing and Imaging of Myeloperoxidase during an Inflammatory … Pubmed: 32126753
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RESPIRATORY RESEARCH The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation … Pubmed: 33148285
J Toxicol Sci Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes Pubmed: 32879255
Theriogenology A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cows Pubmed: 32810791
Scientific Reports Sensitive and rapid lateral-flow assay for early detection of subclinical mammary infection in dairy cows Pubmed: 32636462
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Cells Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in Mice Pubmed: 32580272
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JOURNAL OF SURGICAL RESEARCH Ameliorating Effects of ¦Â-glucan on Epigastric Artery Island Flap Ischemia-Reperfusion Injury 33477077
Stem Cell Research & Therapy Dental pulp stem cells overexpressing hepatocyte growth factor facilitate the repair of DSS-induced ulcerative colitis 33413675
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J Physiol Biochem Strictosamide alleviates the inflammation in an acute ulcerative colitis (UC) model 33595775
J Pediatr Urol Protective effects of hydrogen rich saline solution on ventral penile Mathieu type flap with penile tourniquet application in rats 33608226
J Reprod Immunol JAK3 and PI3K mediates the suppressive effects of interferon tau on neutrophil extracellular traps formation during peri-implantation period 33862433
Br J Pharmacol Macrophage Extracellular Traps Aggravate Iron Overload©\Related Liver Ischemia/Reperfusion Injury 33959955
Nephron Characterization of a Rat Model of Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody-Associated Crescentic Glomerulonephritis 33910203
Exp Eye Res Topical calcitriol application promotes diabetic corneal wound healing and reinnervation through inhibiting NLRP3 inflammasome activation 34144035
Sci Rep Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2¨CSTAT3 pathway 34075160
researchsquare ¦Ê?opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO?1 pathway 33649775
J Inflamm Res Novel 1, 3, 4-Oxadiazole Derivatives of Pyrrolo [3, 4-d] Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced … 34754217
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Experimental and Therapeutic Medicine Blocking tumor necrosis factor-α delays progression of chronic obstructive pulmonary disease in rats through inhibiting MAPK signaling pathway and activating … 34630665
Preprints Hyperactive neutrophils infiltrate vital organs of tumor bearing host and contribute to gradual systemic deterioration with tumor progression 34890699
J Dairy Sci Saccharomyces cerevisiae fermentation products reduce bacterial endotoxin concentrations and inflammation during grain-based subacute ruminal acidosis … Pubmed:34998547
Medicina (Kaunas) Plasma Concentrations of New Biochemical Markers of Atherosclerosis in Patients with Dyslipidemia—A Pilot Study Pubmed:35743980
Reports of Biochemistry & Molecular Biology Serum Myeloperoxidase as A Biomarker of Asthma Severity Among Adults: A Case Control Study Pubmed:35765520
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Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
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APA601Hu61 Active Myeloperoxidase (MPO) Cell culture; Activity Assays.
RPA601Hu02 Recombinant Myeloperoxidase (MPO) Positive Control; Immunogen; SDS-PAGE; WB.
APA601Hu02 Active Myeloperoxidase (MPO) Cell culture; Activity Assays.
PAA601Hu01 Polyclonal Antibody to Myeloperoxidase (MPO) WB; IHC; ICC; IP.
LAA601Hu71 Biotin-Linked Polyclonal Antibody to Myeloperoxidase (MPO) WB; IHC; ICC.
MAA601Hu23 Monoclonal Antibody to Myeloperoxidase (MPO) WB; IHC; ICC; IP.
MAA601Hu21 Monoclonal Antibody to Myeloperoxidase (MPO) WB; IHC; ICC; IP.
MAA601Hu22 Monoclonal Antibody to Myeloperoxidase (MPO) WB; IHC; ICC; IP.
MAA601Hu24 Monoclonal Antibody to Myeloperoxidase (MPO) WB; IHC; ICC; IP.
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KSA601Hu01 ELISA Kit DIY Materials for Myeloperoxidase (MPO) Main materials for "Do It (ELISA Kit) Yourself".