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Recombinant Complement Factor H (CFH)

CF-H; FH; FHL1; ARMD4; ARMS1; CFHL3; HF1; HF2; HUS; H Factor 2; Age-Related Maculopathy Susceptibility 1; Adrenomedullin binding protein

  • Product No.RPA635Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Secreted
  • Predicted Molecular Mass28.7kDa
  • Accurate Molecular Mass29kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla975~Ser1217 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point8.8
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 180  US$ 450  US$ 900  US$ 2700  US$ 6750 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Pediatr Int Atypical hemolytic uremic syndrome: Korean pediatric series PubMed: 25443527
Hernia Circulating matrix metalloproteinases and procollagen propeptides in inguinal hernia Pubmed:29484522
Mikrochim Acta Fluorescent silver nanoclusters as antibody label in a competitive immunoassay for the complement factor H Pubmed: 31187271
Diagnostics Systemic Alterations of Immune Response-Related Proteins during Glaucoma Development in the Murine Model DBA/2J Pubmed: 32585848
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE The importance of sialic acid, pH and ion concentration on the interaction of uromodulin and complement factor H 33788378
Front Immunol A Family Affair: Addressing the Challenges of Factor H and the Related Proteins 33868311
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