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Recombinant Cyclooxygenase-2 (COX 2)

PGG/HS; PGHS2; PHS2; HCox2; PTGS2; Prostaglandin Endoperoxide Synthase 2; Prostaglandin G/H Synthase And Cyclooxygenase; Prostaglandin H2 synthase 2

  • Product No.RPA699Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass31.9kDa
  • Accurate Molecular Mass30kDa(Analysis of differences refer to the manual)
  • Residues & TagsPhe187~Asn425 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point7.4
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 144  US$ 360  US$ 720  US$ 2160  US$ 5400 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Photodermatology, Photoimmunology & Photomedicine Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis Wiley: source
Skin Cancer - MedlinePlus Health Information Molecular mechanisms underlying chemopreventive activities of glycyrrhizic acid against UVB-radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis PubMed: 21545294
Evidence-Based Complementary and Alternative Medicine Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis PubMed: 22888366
Integrative Cancer Therapies Decalepis hamiltonii inhibits tumor progression and metastasis by regulating the inflammatory mediators and nuclear factor κB subunits Pubmed: 24013642
Journal of ethnopharmacology Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats. Pubmed: 24211397
Int J Clin Exp Pathol Relationship between epidermal growth factor receptor (EGFR) mutation and serum cyclooxygenase-2 Level, and the synergistic effect of celecoxib and gefitinib on EGFR expression in non-small cell lung cancer cells PubMed: 26464643
Int J Clin Exp Pathol Monitoring of cyclooxygenase-2 levels can predict EGFR mutations and the efficacy of EGFR-TKI in patients with lung adenocarcinoma PubMed: 26191267
Journal of Biomechanics The shear wave elastic modulus and the increased nuclear factor kappa B(NF-kB/p65) and cyclooxygenase-2 (COX-2) expression in the area of myofascial trigger points activated in a rat model by blunt trauma to the vastus medialis pubmed:29137729
Journal of Global Pharma Technology Inflammatory Response of Annona Muricata Linn Leaves Extract in Colorectal Cancer Patients NCT02439580
International Journal of Molecular Sciences High Expression of IL-1RI and EP2 Receptors in the IL-1β/COX-2 Pathway, and a New Alternative to Non-Steroidal Drugs—Osthole in Inhibition COX-2 Pubmed: 30620999
International Immunopharmacology A novel concept of immunological and allergy interactions in Autism Spectrum Disorders: Molecular, anti-inflammatory effect of osthole Pubmed: 30953868
Reports of Biochemistry & Molecular Biology Evaluation of Serum Cyclooxygenase, Hepcidin Levels in Acute Renal Injury (AKI) Patients Following Cardiac Catheterization
J Ethnopharmacol Isolation and characterization of anti-inflammatory and anti-proliferative compound, for B-cell Non-Hodgkin lymphoma, from Nyctanthes arbor-tristis Linn. Pubmed:35398498
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA699Hu02 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA699Hu03 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA699Hu01 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
PAA699Hu01 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB,IHC
PAA699Hu02 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
MAA699Hu22 Monoclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
SEA699Hu ELISA Kit for Cyclooxygenase-2 (COX 2) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA699Hu Multiplex Assay Kit for Cyclooxygenase-2 (COX 2) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.