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Recombinant Heparanase (HPSE)

HPA; HPR1; HPSE1; HSE1; Endo-glucoronidase;

  • Product No.RPA711Hu02
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus, Secreted, Lysosome
  • Predicted Molecular Mass10.5kDa
  • Accurate Molecular Mass14kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln34~Arg115 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 166  US$ 416  US$ 832  US$ 2496  US$ 6240 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Plos one PG545, a Heparan Sulfate Mimetic, Reduces Heparanase Expression In Vivo, Blocks Spontaneous Metastases and Enhances Overall Survival in the 4T1 Breast Carcinoma Model Plosone: Source
Journal of Medical Science Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity ? uid in women with impaired reproduction Nowinylekarskie:Source
Int J Clin Exp Pathol Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase PubMed: 26191183
Tumour Biology PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection PubMed: 26415733
Journal of Medical Science Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity fluid in women with impaired reproduction article:84
Renal Failure Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage pubmed:28994624
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA711Hu04 Recombinant Heparanase (HPSE) Positive Control; Immunogen; SDS-PAGE; WB.
RPA711Hu02 Recombinant Heparanase (HPSE) Positive Control; Immunogen; SDS-PAGE; WB.
APA711Hu04 Active Heparanase (HPSE) Cell culture; Activity Assays.
APA711Hu01 Active Heparanase (HPSE) Cell culture; Activity Assays.
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APA711Hu61 Active Heparanase (HPSE) Cell culture; Activity Assays.
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RPA711Hu03 Recombinant Heparanase (HPSE) Positive Control; Immunogen; SDS-PAGE; WB.
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PAA711Hu04 Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
PAA711Hu02 Polyclonal Antibody to Heparanase (HPSE) WB,IHC,ICC/IF
PAA711Hu01 Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
PAA711Hu03 Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
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LAA711Hu71 Biotin-Linked Polyclonal Antibody to Heparanase (HPSE) WB; IHC; ICC.
MAA711Hu23 Monoclonal Antibody to Heparanase (HPSE) WB
MAA711Hu22 Monoclonal Antibody to Heparanase (HPSE) WB; IHC; ICC; IP.
MAA711Hu21 Monoclonal Antibody to Heparanase (HPSE) WB,ICC/IF
SEA711Hu ELISA Kit for Heparanase (HPSE) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA711Hu High Sensitive ELISA Kit for Heparanase (HPSE) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA711Hu Multiplex Assay Kit for Heparanase (HPSE) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA711Hu01 ELISA Kit DIY Materials for Heparanase (HPSE) Main materials for "Do It (ELISA Kit) Yourself".