Packages (Simulation)
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Figure . Gene Sequencing (extract)
Image (II)
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SDS-PAGE Image
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Instruction Manual
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Recombinant Kidney Injury Molecule 1 (Kim1)
HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1
- Product No.RPA785Hu02
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- SourceProkaryotic expression
- HostE.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane
- Predicted Molecular Mass53.7kDa
- Accurate Molecular Mass54kDa(Analysis of differences refer to the manual)
- Residues & TagsSer21~Ala240 with N-terminal His and GST Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder
- Purity> 90%
- Isoelectric Point8.6
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Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein. - DownloadInstruction Manual
- UOM 10µg50µg 200µg 1mg 5mg
- FOB
US$ 126
US$ 314
US$ 628
US$ 1884
US$ 4710
For more details, please contact local distributors!
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
GIVEAWAYS
INCREMENT SERVICES
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Endotoxin Removal Kit
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BCA Protein Quantification Kit
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Protein Labeling Customized Service
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Molecular Mass Marker for Protein
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Recombinant Protein Customized Service
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Buffer
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Endotoxin Removal Kit II
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Real Time PCR Experimental Service
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
| Magazine | Citations |
| Clinical Toxicology | Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in patients with acute paraquat intoxication PubMed: 19827907 |
| Pediatric Nephrology | KIM-1 and NGAL: new markers of obstructive nephropathy SpringerLink: v461592787w5488x |
| Pediatric Research | Urinary Neutrophil Gelatinase-Associated Lipocalin at Birth Predicts Early Renal Function in Very Low Birth Weight Infants LWW: 10000 |
| Archives of Medical Science | Markers of kidney function in the elderly in relation to the new CKD-EPI formula for estimation of glomerular filtration rate AMS: source |
| Nephrology | Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content PubMed: 23046363 |
| Nanotoxicology. | Comprehensive assessment of nephrotoxicity of intravenously administered sodium-oleate-coated ultra-small superparamagnetic iron oxide (USPIO) and titanium dioxide (TiO(2)) nanoparticles in rats. PubMed: 23272807 |
| Toxicological Science | A Mouse Diversity Panel Approach Reveals the Potential for Clinical Kidney Injury Due to DB289 Not Predicted by Classical Rodent Models PubMed: PMC3498743 |
| Disease Markers | Interleukin 18 as a Marker of Chronic Nephropathy in Children after Anticancer Treatment Hindawi: 369784 |
| Journal of Biomarkers | Urinary Measurement of Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Helps Diagnose Acute Pyelonephritis in a Preclinical Model Hindawi: 413853 |
| Advances in Life Science and Technology | Kidney injury molecule-1: a urinary biomarker for contrast induced acute kidney injury. Iiste: Source |
| Nephrology | Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant Pubmed: 24325180 |
| Nephrology | Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content. Pubmed: 23046363 |
| BioMed Research International | The Renal Effects of Vanadate Exposure: Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies Hindawi: 740105 |
| Life Sci. | Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat model Pubmed:25476829 |
| Diabetes & Vascular Disease Research | Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats Sagepub:Source |
| 临床儿科杂志 | 中性粒细胞明胶酶相关脂质运载蛋白、肾损伤分子1和白介素18 在诊断心肺分流术后急性肾损伤中的意义 Jcp-Sh:Source |
| Nephrology (Carlton). | Tubular urinary biomarkers do not identify aetiology of acute kidney injury in kidney transplant recipients Pubmed:24666430 |
| PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion Pubmed:24816434 |
| BMC Nephrology | SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial Pubmed:24996842 |
| Pediatric Nephrology | The diagnosis of febrile urinary tract infection in children may be facilitated by urinary biomarkers Pubmed:25127917 |
| Inflammation.? | Systemic and Flap Inflammatory Response Associates with Thrombosis in Flap Venous Crisis Pubmed:25448261 |
| Transworld Medical Journal | Kidney injury molecule-1: A urinary biomarker for contrast-induced acute kidney injury Tmjournals:Source |
| Int J Clin Exp Pathol | Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis PubMed: 26191125 |
| Int J Clin Exp Pathol | Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice PubMed: 26045773 |
| Mol Med Rep | Vorinostat protects against calcium oxalate-induced kidney injury in mice PubMed: 26095064 |
| Pediatr Nephrol | Role of new biomarkers for predicting renal scarring in vesicoureteral reflux: NGAL, KIM-1, and L-FABP PubMed: 26324091 |
| Journal of Pediatric Urology | Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis PubMed: 26096437 |
| Am J Physiol Renal Physiol | Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the Kidney PubMed: 26672616 |
| Mol Med Rep. | Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti‑inflammatory, and anti‑apoptotic activities. Pubmed:27082705 |
| Nephrol. Dial. Transplant. | Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models Pubmed:26908768 |
| J Clin Lab Anal. | Kidney Injury Molecule Levels in Type 2 Diabetes Mellitus Pubmed:27132791 |
| Med Sci Monit. | Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Model pmc:PMC4754091 |
| Diabetes. | Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis Pubmed:26822084 |
| Sci Rep. | Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice Pubmed:27226136 |
| Journal of Applied Life Sciences International | Vitamins C and E Alleviate Nephrotoxicity-induced by Potassium Bromate in Rats Barakat812016JALSI28698.pdf |
| Oxidative Medicine and Cellular Longevity | Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model. pubmed:28053694 |
| Molecular Medicine Reports | Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via itsantioxidant, anti‑inflammatory, and anti‑apoptotic activities. pubmed:27082705 |
| Journal of Agricultural and Food Chemistry | Protective Effects of DHA-PC against Vancomycin-Induced Nephrotoxicity through the Inhibition of Oxidative Stress and Apoptosis in BALB/c Mice pubmed:29254330 |
| Clin Exp Pharmacol Physiol. | Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats. pubmed:29027259 |
| Nephron - Physiology | Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise 10.1159/000481179 |
| Cellular Physiology and Biochemistry | Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats … Pubmed:29550811 |
| Frontiers in Pharmacology | Exploring the therapeutic mechanism of Desmodium styracifolium on oxalate crystal-induced kidney injuries using comprehensive approaches based on … Pubmed:29950996 |
| Molecules | Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic Nephropathy Pubmed:29642511 |
| American Journal of Physiology-Regulatory Integrative and Comparative Physiology | Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice Pubmed:29443547 |
| Biological Trace Element Research | Effect of Aqueous Extract of Glycyrrhiza glabra on the Biochemical Changes Induced by Cadmium Chloride in Rats Pubmed: 30251228 |
| Cancer Research and Treatment | A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1(KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo |
| Archives of Medical Science | Urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, N-acetyl-β-D-glucosaminidase levels and mortality risk in septic patients with … Pubmed: 30393493 |
| Biological & Pharmaceutical Bulletin | UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury Pubmed: 30381664 |
| Kidney and Blood Pressure Research | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy Pubmed: 30504713 |
| Clinica Chimica Acta | Urine markers of renal tubular injury in idiopathic membranous nephropathy: A cross sectional study Pubmed: 30684459 |
| BMC Complementary and Alternative Medicine | Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine Pubmed: 30871515 |
| 2.583 | Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors Doi: BioMed Research International |
| Naunyn-Schmiedeberg's archives of pharmacology | Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade Pubmed: 31197431 |
| Egyptian Journal of Zoology | Effect of Cucumis melo var. flexuosus leaves extract on renal oxidative injury and inflammation in diabetic male albino rats |
| Environment International | Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures Pubmed: 31639605 |
| Bioscience Reports | page Metabolomics study of fasudil on cisplatin-induced kidney injury Pubmed: 31670380 |
| life sciences | MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury Pubmed: 31790686 |
| Arch Physiol Biochem | Protective effect of saxagliptin against renal ischaemia reperfusion injury in rats Pubmed: 31979992 |
| clinical science | Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin D Pubmed: 31943002 |
| LIFE SCIENCES | Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway Pubmed: 32798557 |
| INTERNATIONAL UROLOGY AND NEPHROLOGY | Serum NGAL, KIM-1, IL-18, L-FABP: new biomarkers in the diagnostics of acute kidney injury (AKI) following invasive cardiology procedures Pubmed: 32557377 |
| Journal of Pediatric Urology | Can Serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Help in Decision Making for Surgery in Antenatally Dedected … Pubmed: 33139211 |
| Ratlarda sodyum florid ile oluşturulan toksikasyonda Karvakol'ün böbrekler üzerine etkisi | |
| Rationale and design of the intervention in PHOspholamban RElated CArdiomyopathy STudy (i-PHORECAST) | |
| Pediatr Int | Early Kidney Injury in Immunoglobulin A Vasculitis: Role of Renal Biomarkers 33423326 |
| J Int Med Res | Value of urinary kidney injury molecule-1 levels in predicting acute kidney injury in very low birth weight preterm infants 33372811 |
| Biomed Res Int | Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury 33604384 |
| Nutrients | Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide 33922959 |
| J Am Soc Nephrol | Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI 34127536 |
| Heliyon | Anti-oxidant impact of Lisinopril and Enalapril against acute kidney injury induced by doxorubicin in male Wistar rats: involvement of kidney injury molecule-1 33506137 |
| Journal of Pharmacological Sciences | Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-¦ÊB/HMGB-1 trajectories 34030796 |
| Int Urol Nephrol | Could urinary kidney injury molecule-1 be a good marker in subclinical acute kidney injury in mild to moderate COVID-19 infection? 34213713 |
| Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … 34169407 |
| iscience | Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure 34820603 |