≡

Recombinant C Reactive Protein (CRP)

C-RP; PTX1; Pentraxin-Related; Pentraxin 1

  • Product No.RPA821Mu02
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass53.1kDa
  • Accurate Molecular Mass53kDa(Analysis of differences refer to the manual)
  • Residues & TagsHis20~Ser225 with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point5.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 140  US$ 350  US$ 700  US$ 2100  US$ 5250 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Journalof Vascular Research Effect of Hirulog-Like Peptide on Balloon Catheter Injury-Induced Neointimal Formation in Femoral Arteries of Minipigs and Relationship with Inflammatory Mediators Karger: 000257340
Journal of Pharmacology and Experimental Therapeutics Successful Treatment of Acute Lung Injury with Pitavastatin in Septic Mice: Potential Role of Glucocorticoid Receptor Expression in Alveolar Macrophages Aspet: 171462
Experimental Animals Anti-Inflammatory Effect of Guan-Xin-Er-Hao via the Nuclear Factor-Kappa B Signaling Pathway in Rats with Acute Myocardial Infarction Jstage: source
Neuroscience In vivo protective effect of ferulic acid against noise-induced hearing loss in the guinea-pig PubMed: 20600667
Heart and Vessels Metformin inhibits nuclear factor κB activation and decreases serum high-sensitivity C-reactive protein level in experimental atherogenesis of rabbits SpringerLink: pt732478620w1528
Plos one Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial PubMed: 23516412
Psychosomatic Medicine Unpredictable chronic mild stress promotes atherosclerosis in high cholesterol-fed rabbits PubMed: 22753638
PLOS ONE Protective Effect of Curcumin on Pulmonary and Cardiovascular Effects Induced by Repeated Exposure to Diesel Exhaust Particles in Mice PlosOne: Source
BMC Neurology Relationships among serum C-reactive protein, receptor for advanced glycation products, metabolic dysfunction, and cognitive impairments PubMed: PMC3765839
Particle and fibre toxicology, Impact of experimental type 1 diabetes mellitus on systemic and coagulation vulnerability in mice acutely exposed to diesel exhaust particles PubMed: PMC3641025
Clinics Changes in body weight, C-reactive protein, and total adiponectin in non-obese women after 12 months of a small-volume, home-based exercise program PubMed: PMC3752622
PLoS One Pre-Pubertal Children Born Post-Term Have Reduced Insulin Sensitivity and Other Markers of the Metabolic Syndrome PubMed: PMC3698136
Scientific Report Among overweight middle-aged men, first-borns have lower insulin sensitivity than second-borns Pubmed: 24503677
International Urology Nephrology Perirenal fat associated with microalbuminuria in obese rats Pubmed: 24526332
AJBM Effect of caffeic acid on doxorubicin induced cardiotoxicity in rats Ajbm: Source
Journal of Molecular and Cellular Cardiology Effect of high free fatty acids on the anti-contractile response of perivascular adipose tissue in rat aorta Pubmed: 23939490
PLoS One. Flos Lonicera Ameliorates Obesity and Associated Endotoxemia in Rats through Modulation of Gut Permeability and Intestinal Microbiota Plos: Source
Fundamental & Clinical Pharmacology The determination of histopathological and biochemical effects of the rabbit knee joint injected dexketoprofen trometamol Onlinelibrary: fcp.12074
Mainz Identifizierung neuer potentieller Biomarker für das Kolonkarzinom sowie dessen Vorstufen Info:Source
Int J Clin Exp Med. Celastrol may have an anti-atherosclerosis effect in a rabbit experimental carotid atherosclerosis model Pubmed:Pmc4132129
International Urology and Nephrology As If Biomarker Discovery Isn&#039;t Hard Enough: The Consequences of Poorly Characterized Reagents Pubmed:24305687
Nutr Res. Curcumin attenuates adhesion molecules and matrix metalloproteinase expression in hypercholesterolemic rabbits Pubmed:25282128
Journal of Obstetrics and Gynaecology Research Regression of experimental endometriotic implants in a rat model with the angiotensin II receptor blocker losartan Pubmed:25302540
Chemical Research in Toxicology Sub-chronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwall Carbon Nanotubes by Intratracheal Instillation Pubmed:25580880
Journal of Applied Toxicology Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits Pubmed:25619500
Cellular Physiology and Biochemistry Short-Term Nose-Only Water-Pipe (Shisha) Smoking Exposure Accelerates Coagulation and Causes Cardiac Inflammation and Oxidative Stress in Mice Pubmed:25634761
Food and Chemical Toxicology Consumption of orange fermented beverage reduces cardiovascular risk factors in healthy mice Pubmed:25666657
Cellular Physiology and Biochemistry Induction of Haemeoxygenase-1 Improves FFA-Induced Endothelial Dysfunction in Rat Aorta Pubmed:25766533
天津中医药大学学报 巨噬细胞及其相关因子在家兔不稳定斑块中的作用及其机制 Paper:Source
Mediators of Inflammation Effects of Intravenous Injection of PubMed: 26063970
Am J Physiol Heart Circ Physiol Irisin improves endothelial function in obese mice through the AMPK-eNOS pathway PubMed: 26371167
Cell Physiol Biochem Induction of Haemeoxygenase-1 Directly Improves Endothelial Function in Isolated Aortas from Obese Rats through the Ampk-Pi3k/Akt-Enos Pathway PubMed: 26160485
Exp Physiol Renal protective effects of induction of haem oxygenase-1 combined with increased adiponectin on the glomerular vascular endothelial growth factor–nitric oxide axis in obese rats PubMed: 25959017
Clin Oral Investig Can apical periodontitis affect serum levels of CRP, IL-2, and IL-6 as well as induce pathological changes in remote organs? PubMed: 26556576
Chemical Research in Toxicology Subchronic Toxicity and Cardiovascular Responses in Spontaneously Hypertensive Rats after Exposure to Multiwalled Carbon Nanotubes by Intratracheal Instillation PubMed: 25580880
Acta Biomater Resveratrol Inhibited Inflammation andAlveolar Bone Loss in Periodontitis PubMed: 26497626
Archives of Physiology and Biochemistry Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder Pubmed:26934364
Journal of Functional Foods Orange beverage ameliorates high-fat-diet-induced metabolic disorder in mice article:S1756464616300688
Medical Science Monitor Variation of Circulating Inflammatory Mediators in Staphylococcus aureus and Escherichia coli BloodstreamInfection. Pubmed:26772168
J Diabetes Res.  Central Administration of Galanin Receptor 1 Agonist Boosted Insulin Sensitivity in Adipose Cells of Diabetic Rats pmc:PMC4835658
Asian J Pharm Clin Res THE ANTI-HYPERCHOLESTEROLEMIC EFFECT OF ULVAN POLYSACCHARIDE EXTRACTED FROM THE GREEN ALGA ULVAFASCIATA ON AGED HYPERCHOLESTEROLEMIC RATS journals:10835
J Bone Miner Res Fat and Sucrose Intake Induces Obesity‐Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats Pubmed:26175082
Naunyn-Schmiedeberg's Archives of Pharmacology Combined oral contraceptive-induced hypertension is accompanied by endothelial dysfunction and upregulated intrarenal angiotensin II type 1 receptor gene expression pubmed:27447455
Journal of Coastal Life Medicine Cardioprotective and renoprotective effects of Cocos nucifera water in offspring of high fat diet fed Wistar rat dams qk:20168
Journal of Functional Foods Eicosapentaenoic acid-enriched phospholipids improve atherosclerosis by mediating cholesterol metabolism S1756464617300890
Environmental toxicology and pharmacology Combined oral contraceptive and nitric oxide synthesis inhibition synergistically causes cardiac hypertrophy and exacerbates insulin resistance in female rats. pubmed:28376377
Andrology Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis … doi:10.1111
Journal of Diabetes Research Central administration of galanin receptor 1 agonist boosted insulin sensitivity in adipose pubmed:27127795
Therapeutics and Clinical Risk Management Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in an Indian population. pubmed:27540296
Veterinary World Acute phase response in lame crossbred dairy cattle pubmed:27956769
J Ethnopharmacol Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis. pubmed:27880884
SHOCK INTERLEUKIN-1 RECEPTOR 2: A NEW BIOMARKER FOR SEPSIS DIAGNOSIS AND GRAM-NEGATIVE/GRAM-POSITIVE BACTERIAL DIFFERENTIATION pubmed:27984536
International Surgery PROCALCITONIN, C-REACTIVE PROTEIN AND FIBRINOGEN LEVELS IN CASES WITH MECHANIC BOWEL OBSTRUCTION AND THEIR CHANGE IN RELATION TO THE DURATION OF OBSTRUCTION: AN EXPERIMENTAL STUDY 10.3892/ol.2017.7301
CORONARY ARTERY DISEASE Relationship of mean platelet volume to lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris pubmed:28678144
Biomedicine & Pharmacotherapy Protective effect of α–lipoic acid against spleen toxicity of dimethylnitrosamine in male mice: Antioxidant and ultrastructure approaches pubmed:29031205
PLoS One The effects of non-surgical periodontal treatment on glycemic control, oxidative stress balance and quality of life in patients with type 2 diabetes: A randomized clinical trial pubmed:29145468
Poultry Science The effect of DL-, L-isomers and DL-hydroxy analog administered at 2 levels as dietary sources of methionine on the metabolic and antioxidant parameters and growth performance of turkeys 10.3382/ps/pex099
Oncotarget The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis. pubmed:29029533
International Journal of Cuban Health & Medicine Anemia and Iron Deficiency Related to Inflammation, Helicobacter pylori Infection and Adiposity in Reproductive-age Cuban Women 10.1590/MEDICC.2017.1902030004 
Korean Journal of Internal Medicine The relationship between anti-C-reactive protein and disease activity in patients with systemic lupus erythematosus. pubmed:28352058
Biomedical and Environmental Sciences Grape Seed Procyanidin Extract Reduces Arsenic-Induced Renal Inflammatory Injury in Male Mice. pubmed:28756814
Pharmacological reports Anti-inflammatory and antithrombotic effects of nicotine exposure in oral contraceptive-induced insulin resistance are glucocorticoid-independent pubmed:28349880
Nature Communications A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense Pubmed:29410422
International Journal of Obesity Leptin alleviates intestinal mucosal barrier injury and inflammation in obese mice with acute pancreatitis Pubmed:29934609
Molecular Nutrition & Food Research The Protective Activities of Dietary Sea Cucumber Cerebrosides Against Atherosclerosis Through Regulating Inflammation and Cholesterol Metabolism in Male Mice Pubmed:29883529
Oxidative Medicine and Cellular Longevity Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague … Pubmed:29849871
Nutrients L-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function Pubmed:29473908
Journal of Functional Foods Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties 10.1016:j.jff.2018.07.046
Veterinary immunology and immunopathology Generation and validation of novel anti-bovine CD163 monoclonal antibodies ABM-1A9 and ABM-2D6 Pubmed:29571519
Journal of Experimental Animal Science  Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway Pubmed:29526865
Journal of Young Pharmacists Anti-Inflammatory Activity of Combined Aerodisperse System in the Conditions of Experimental Cervical Lymphadenite :
Journal of Pharmacological Sciences Improved endogenous epoxyeicosatrienoic acid production mends heart function via increased PGC 1α-mitochondrial functions in metabolic syndrome Pubmed: 30342783
The Egyptian Rheumatologist Sonographic synovitis in primary knee osteoarthritis patients and its relation to biomarkers of inflammation and oxidative stress Doi: 10.1016/j.ejr.2018.12.004
West Indian Medical Journal Plasma Cellular Hypoxia, Mitochondrial Dysfunction, Disease Risk and Prognostic Factors in Type 2 Diabetic Patients in Saudi Arabia.
Nutrition & Metabolism L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women Pubmed: 30485835
The Egyptian Rheumatologist The Egyptian Rheumatologist
Experimental Biology and Medicine Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signaling Pubmed: 30869553
International Journal of Inflammation Morphological Characteristics of the Thymus and Spleen and the Subpopulation Composition of Lymphocytes in Peripheral Blood during Systemic Inflammatory …
Journal of Central European Agriculture Novel assay for the detection of CRP protein in rabbit leukocytes using flow cytometry
Journal of Clinical Medicine Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis Pubmed: 31072030
Journal of Applied Pharmaceutical Science Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
Food & Function Eicosapentaenoic acid in the form of phospholipid exerts superior anti-atherosclerosis effects than its triglyceride form in ApoE-/-mice
Journal of Central European Agriculture Novel assay for the detection of CRP protein in rabbit leukocytes using flow cytometry/Nova metoda detekcie CRP proteinu na kralicich leukocytoch pomocou …
Food and Chemical Toxicology The potential efficacy of dietary fatty acids and fructose induced inflammation and oxidative stress on the insulin signaling and fat accumulation in mice Pubmed: 31672515
Journal of Controlled Release Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury Pubmed: 31783047
Nutrients Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes Rats Pubmed: 31887996
Food & Function Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial Pubmed: 32044905
JOURNAL OF HAZARDOUS MATERIALS Silica nanoparticles induce JNK-mediated inflammation and myocardial contractile dysfunction Pubmed: 32036317
Cell Transplant The Efficacy of Autologous Myoblast Sheet Transplantation to Prevent Perforation After Duodenal Endoscopic Submucosal Dissection in Porcine Model Pubmed: 33121270
Nanotoxicology miR-205/IRAK2 signaling pathway is associated with urban airborne PM2.5-induced myocardial toxicity Pubmed: 32880512
Journal of the American Society of Echocardiography Protective Effects of Statin and Angiotensin Receptor Blocker in a Rat Model of Doxorubicin-and Trastuzumab-Induced Cardiomyopathy Pubmed: 32778498
disease markers Association between Plasma Sestrin2 Levels and the Presence and Severity of Coronary Artery Disease Pubmed: 32670435
Scientific Reports Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in rats Pubmed: 32616735
animal reproduction science Quantifying the C-reactive protein concentrations of uterine lavage samples in postpartum dairy cows Pubmed: 32408965
ANNALS OF TRANSLATIONAL MEDICINE Serum levels of olfactomedin 4: a biomarker for asthma control state in asthmatics Pubmed: 32395538
nutrition Validation and adaptation of the Empirical Dietary Inflammatory Pattern (EDIP) across nations: a test case. Pubmed: 32563770
European Journal of Biology Effects of Tempol in Lipopolysaccharide-Induced Liver Injury
Possible Role of Statins on the Inflammatory Biomarkers in Patients With Periodontal Disease: A Cross-Sectional Study
International Journal of Oral Science Endothelin-1 is a surrogate biomarker link severe periodontitis and endothelial dysfunction in hypertensive patients: The potential nexus
Indian Journal of Animal Research Effect of claw disorders on haemato-biochemical parameters and acute phase protein levels in crossbred cattle
Lateral Flow Immunosensor for Ferritin Based on Dual Signal-Amplified Strategy by Rhodium Nanoparticles
Early label-free analysis of mitochondrial redox states by Raman spectroscopy predicts septic outcomes
МАРКЕРЫ КОСТНОГО РЕМОДЕЛИРОВАНИЯ ПРИ ЗАМЕЩЕНИИ ДЕФЕКТАТРАБЕКУЛЯРНОЙ КОСТНОЙ ТКАНИ РЕЗОРБИРУЕМЫМИ И …
J Transl Med Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Use of Fourier-Transform Infrared Spectroscopy (FT-IR) for Monitoring Experimental Helicobacter pylori Infection and Related Inflammatory Response in Guinea Pig?¡­ 33396581
Sci Rep Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats 33833309
Mol Med Rep Baicalin relieves Mycoplasma pneumoniae infection?induced lung injury through regulating microRNA?221 to inhibit the TLR4/NF?¦ÊB signaling pathway 34109422
Nutrients Prevalence and Factors Associated with Iron Deficiency and Anemia among Residents of Urban Areas of S?o Paulo, Brazil 34072813
peerj Perfluorooctane sulfonate exerts inflammatory bowel disease-like intestinal injury in rats 33510972
Biomed Pharmacother Intravenous ferric carboxymaltose does not provide benefits in reperfused acute myocardial infarction in the rat with normal iron status 34243097
Aging Pim-2 kinase inhibits inflammation by suppressing the mTORC1 pathway in atherosclerosis 34547720
Analytical and Bioanalytical Chemistry Nets of biotin-derived gold nanoparticles as a label for the C-reactive protein immunoassay 34559243
J Oleo Sci Cardio-protective and Anti-atherosclerosis Effect of Crocetin on Vitamin D3 and HFD-induced Atherosclerosis in Rats 34615830
Medicine Early-stage serum Stanniocalcin 1 as a predictor of outcome in patients with aneurysmal subarachnoid hemorrhage Pubmed:34941085
Talanta A rapid fluorescent aptasensor for point-of-care detection of C-reactive protein Pubmed:35714415
Experimental and Therapeutic Medicine Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosis Pubmed:35126715
Sensors and Actuators B: Chemical A Two-step Competition Assay for Visual, Sensitive and Quantitative C-reactive Protein Detection in Low-cost Microfluidic Particle Accumulators
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
APA821Mu02 Active C Reactive Protein (CRP) Cell culture; Activity Assays.
RPA821Mu01 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
APA821Mu62 Active C Reactive Protein (CRP) Cell culture; Activity Assays.
APA821Mu61 Active C Reactive Protein (CRP) Cell culture; Activity Assays.
RPA821Mu02 Recombinant C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
EPA821Mu61 Eukaryotic C Reactive Protein (CRP) Positive Control; Immunogen; SDS-PAGE; WB.
PAA821Mu02 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
PAA821Mu01 Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
LAA821Mu81 FITC-Linked Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IF.
LAA821Mu71 Biotin-Linked Polyclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC.
MAA821Mu22 Monoclonal Antibody to C Reactive Protein (CRP) WB; IHC; ICC; IP.
SEA821Mu ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection.
MEA821Mu Mini Samples ELISA Kit for C Reactive Protein (CRP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA821Mu Multiplex Assay Kit for C Reactive Protein (CRP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA821Mu01 ELISA Kit DIY Materials for C Reactive Protein (CRP) Main materials for "Do It (ELISA Kit) Yourself".