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Recombinant Selenoprotein P1, Plasma (SEPP1)

SEPP; SeP; SEP-P1; SELP

  • Product No.RPB809Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass27.1kDa
  • Accurate Molecular Mass29kDa(Analysis of differences refer to the manual)
  • Residues & TagsTyr60~Ser263 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point7.2
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 140  US$ 350  US$ 700  US$ 2100  US$ 5250 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
The Journal of Clinical Endocrinology & Metabolism Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis PubMed: 21677040
Diabetes & metabolism journal Increased Selenoprotein P Levels in Subjects with Visceral Obesity and Nonalcoholic Fatty Liver Disease PubMed: 23439771
Journal of Pediatric Biochemistry Trace elements, heavy metals and vitamins in Egyptian school children with iron deficiency anemia Metapress:Source
Journal of Trace Elements in Medicine and Biology Selenium and its relationship with selenoprotein P and glutathione peroxidase in children and adolescents with Hashimoto&#039;s thyroiditis and hypothyroidism PubMed: 26854239
OBES RES CLIN PRACT/OBESITY RESEARCH & CLINICAL PRACTICE Selenoprotein P is elevated in individuals with obesity, but is not independently associated withinsulin resistance. pubmed:27524654
Annals of Nutrition and Metabolism Acute Overfeeding Does Not Alter Liver or Adipose Tissue-Derived Cytokines in HealthyHumans. pubmed:27832637
European Journal of Nutrition DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: ashort-term supplementation trial with respect to GPX1 and SEPP1 polymorphism. pubmed:26658762
South. Clin. Ist. Euras. Evaluation of the Relationship Between Insulin Resistance and Selenoprotein P in Patients with Polycystic Ovary Syndrome DOI: 10.14744/scie.2017.87597
Arch Endocrinol Metab Serum selenium and selenoprotein-P levels in autoimmune thyroid dieases patients in a select center a transversal study DOI: 10.1590/2359-3997000000309
British Journal of Nutrition Selenium, selenoproteins and selenometabolites in mothers and babies at the time of birth pubmed:28534447
Journal of Trace Elements in Medicine and Biology Biomarkers of selenium status and antioxidant effect in workers occupationally exposed to mercury Pubmed:29895371
Biological & Pharmceutical Bulletin Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits Pubmed:29709922
Diabetologia Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus Pubmed: 30470912
Biological Trace Element Research Selenium Levels in Community Dwellers with Type 2 Diabetes Mellitus Pubmed: 30725267
Advances in Medical Sciences Can hepatokines be regarded as novel non-invasive serum biomarkers of intrahepatic lipid content in obese children? Pubmed: 30921653
Acute swimming exercise, but not exposure to moderate hypoxic conditions reduces circulating selenoprotein P levels in short-term, high-fat diet-fed rats Pubmed: 31236416
Hormones Selenium and selenoprotein P in nonalcoholic fatty liver disease Pubmed: 31493247
Bull Environ Contam Toxicol Soil Selenium Concentration and Residents Daily Dietary Intake in a Selenosis Area: A Preliminary Study in Yutangba Village, Enshi City, China Pubmed: 32909074
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Higher Serum Selenoprotein P Level as a Novel Inductor of Metabolic Complications in Psoriasis Pubmed: 32605214
Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function
Nat Immunol Selenium–GPX4 axis protects follicular helper T cells from ferroptosis 34413521
Reviews in Cardiovascular Medicine Selenoprotein P-1 (SEPP1) as An Early Biomarker of Acute Kidney Injury in Patients Undergoing Cardiopulmonary Bypass
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB809Ra01 Recombinant Selenoprotein P1, Plasma (SEPP1) Positive Control; Immunogen; SDS-PAGE; WB.
PAB809Ra01 Polyclonal Antibody to Selenoprotein P1, Plasma (SEPP1) WB; IHC; ICC; IP.
MAB809Ra21 Monoclonal Antibody to Selenoprotein P1, Plasma (SEPP1) WB; IHC; ICC; IP.
SEB809Ra ELISA Kit for Selenoprotein P1, Plasma (SEPP1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB809Ra Multiplex Assay Kit for Selenoprotein P1, Plasma (SEPP1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.