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Recombinant Lysyl Oxidase (LOX)

Protein-Lysine 6-Oxidase

  • Product No.RPC580Hu02
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass32.7kDa
  • Accurate Molecular Mass33kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsp169~Tyr417 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point6.3
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 164  US$ 410  US$ 820  US$ 2460  US$ 6150 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
American Journal of Hematology The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms. PubMed: 23494965
Current Eye Research High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells Pubmed: 22966818
European Journal of Surgical Oncology Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed: 24246612
Vaccine Copia autorizada por CDR Ingentaconnect: Source
Arthritis & Rheumatology Lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis Pubmed: 24574233
Eur J Surg Oncol.? Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed:Pmc4237001
BMC Cancer. Ionizing radiation induces tumor cell lysyl oxidase secretion Pubmed:Pmc4223762
DNA Cell Biol. Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer Pubmed:24945327
scandinavian journal of immunology Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis PubMed: 26095613
Curr Eye Res Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation Pubmed:27116380
journal of bone and mineral metabolism LOX Fails to Substitute for RANKL in Osteoclastogenesis. pubmed:27606829
38 Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases. pubmed:28445728
Molecular Medicine Reports Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritis pubmed:28901438
Revista Española de Cardiología (English Edition) A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction Pubmed:29807761
Molecular Medicine Reports Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro Pubmed:29393489
Thyroid Lysyl Oxidase is a key player in BRAF/MAPK pathway-driven thyroid cancer aggressiveness Pubmed: 30398411
Am J Physiol Lung Cell Mol Physiol Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis. Pubmed: 33026236
J Am Heart Assoc Collagen Cross©\Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy 33356379
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
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