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Recombinant Serglycin (SRGN)

PRG; PPG; PRG1; proteoglycan 1, secretory granule

  • Product No.RPC869Ra02
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Cytoplasm, Golgi apparatus, Extracellular matrix
  • Predicted Molecular Mass45.8kDa
  • Accurate Molecular Mass46kDa(Analysis of differences refer to the manual)
  • Residues & TagsTyr27~Ile179 with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point4.0
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 142  US$ 355  US$ 710  US$ 2130  US$ 5325 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Irish Journal of Medical Science The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis Pubmed: 30536194
MOLECULAR AND CELLULAR BIOCHEMISTRY SRGN, a new identified shear-stress-responsive gene in endothelial cells Pubmed: 32712749
Theranostics Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer 33456569
CELLULAR ONCOLOGY Cancer©\associated fibroblasts secrete hypoxia©\induced serglycin to promote head and neck squamous cell carcinoma tumor cell growth in vitro and in vivo by ¡­ 33651283
Cell Death Dis Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone 34556636
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPC869Ra02 Recombinant Serglycin (SRGN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC869Ra01 Recombinant Serglycin (SRGN) Positive Control; Immunogen; SDS-PAGE; WB.
PAC869Ra02 Polyclonal Antibody to Serglycin (SRGN) WB; IHC; ICC; IP.