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Recombinant Glutathione Peroxidase 3, Plasma (GPX3)

GSHPX3; GPx-P; GSHPx-P; GPXP; Plasma glutathione peroxidase; Extracellular glutathione peroxidase

  • Product No.RPC992Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass9.5kDa
  • Accurate Molecular Mass10kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln21~Tyr72 with N-terminal His Tag
  • Buffer Formulation100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point7.1
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 168  US$ 420  US$ 840  US$ 2520  US$ 6300 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Reproduction Alteration in the intrafollicular thiol–redox system in infertile women with endometriosis Pubmed:25376627
international journal of cardiology Endothelial function impairment in STEMI patients with out-of-hospital cardiac arrest under therapeutic hypothermia treatment. pubmed:28087172
Current Alzheimer Research Comparison of Extracellular and Intracellular Blood Compartments Highlights Redox Alterations in Alzheimer's and Mild Cognitive Impairment Patients. pubmed:27748187
Frontiers in Microbiology Burn Serum Increases Staphylococcus aureus Biofilm Formation via Oxidative Stress. pubmed:28702016
Clinical and Translational Oncology Hydrogen peroxide-induced mitophagy contributes to laryngeal cancer cells survival via the upregulation of FUNDC1 Pubmed: 30284230
Toxicological Sciences Kidney toxicity and response of selenium containing protein-glutathione peroxidase (Gpx3) to CdTe QDs on different levels Pubmed: 30535317
Available at SSRN 3234834 Human Plasma Protein (s) Based Conceptual Diagnostic Tool for Altitude-Acclimation Assessment
The Journal of Nutritional Biochemistry Dietary selenium deficiency or selenomethionine excess drastically alters organ selenium contents without altering the expression of most selenoproteins in mice
Ecotoxicology and Environmental Safety Molecular mechanisms of lead-induced changes of selenium status in mice livers through interacting with selenoprotein P
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY In vivo and in vitro studies on inactivation of selenium containing protein-glutathione peroxidase 3 in mice nephrocytes caused by lead Pubmed: 32678766
Nat Immunol Selenium–GPX4 axis protects follicular helper T cells from ferroptosis 34413521
Eberhard Karls University Experimental nephrotic syndrome in mice with an inducible deletion of podocin and the role of plasminogen in sodium retention
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
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EPC992Hu61 Eukaryotic Glutathione Peroxidase 3, Plasma (GPX3) Positive Control; Immunogen; SDS-PAGE; WB.
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PAC992Hu02 Polyclonal Antibody to Glutathione Peroxidase 3, Plasma (GPX3) WB; IHC; ICC; IP.
MAC992Hu22 Monoclonal Antibody to Glutathione Peroxidase 3, Plasma (GPX3) WB; IHC; ICC; IP.
SEC992Hu ELISA Kit for Glutathione Peroxidase 3, Plasma (GPX3) Enzyme-linked immunosorbent assay for Antigen Detection.
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