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Recombinant Janus Kinase 2 (JAK2)

JTK10; Tyrosine-protein kinase JAK2

  • Product No.RPF494Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus, Cytoplasm
  • Predicted Molecular Mass34.9kDa
  • Accurate Molecular Mass35kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsn508~Ala800 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point6.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 184  US$ 460  US$ 920  US$ 2760  US$ 6900 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Scientific Reports Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus. pubmed:28336920
Molecular Neurobiology Erythropoietin Rescues Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via the EPO-R/JAK2/STAT5/PI3K/Akt/GSK-3β Pathway pubmed:28488208
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPF494Hu01 Recombinant Janus Kinase 2 (JAK2) Positive Control; Immunogen; SDS-PAGE; WB.
APF494Hu01 Active Janus Kinase 2 (JAK2) Cell culture; Activity Assays.
PAF494Hu01 Polyclonal Antibody to Janus Kinase 2 (JAK2) WB; IHC; ICC/IF
LAF494Hu71 Biotin-Linked Polyclonal Antibody to Janus Kinase 2 (JAK2) WB; IHC; ICC.
SEF494Hu ELISA Kit for Janus Kinase 2 (JAK2) Enzyme-linked immunosorbent assay for Antigen Detection.