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Recombinant Secreted Frizzled Related Protein 4 (SFRP4)

FRP-4; FRPHE; Frizzled protein, human endometrium

  • Product No.RPF878Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass16.0kDa
  • Accurate Molecular Mass19kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal27~Asp154 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point4.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 140  US$ 350  US$ 700  US$ 2100  US$ 5250 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Endocrine Journal Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance PubMed: 26041556
Horm Metab Res. Secreted Frizzled-Related Protein 4 (SFRP4) is Elevated in Patients with Diabetes Mellitus Pubmed:26882051
Obesity (Silver Spring).  Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity pubmed:27768254
Obesity Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans Pubmed:29427376
Novel marker for gestational diabetes patent:US20180059122A1
British Journal Of Nutrition A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile Pubmed: 30375290
American Journal of Cancer Research SFRP4 is a prognostic marker and correlated with Treg cell infiltration in pancreatic ductal adenocarcinoma Pubmed: 30906634
Diabetologia Effects of long-term exercise on plasma adipokine levels and inflammation-related gene expression in subcutaneous adipose tissue in sedentary dysglycaemic … Pubmed: 31011777
PLoS One First trimester secreted Frizzled-Related Protein 4 and other adipokine serum concentrations in women developing gestational diabetes mellitus Pubmed: 33206702
Gastric Cancer SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence 33277667
Diabetology Early Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop …
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPF878Mu02 Recombinant Secreted Frizzled Related Protein 4 (SFRP4) Positive Control; Immunogen; SDS-PAGE; WB.
RPF878Mu01 Recombinant Secreted Frizzled Related Protein 4 (SFRP4) Positive Control; Immunogen; SDS-PAGE; WB.
PAF878Mu01 Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) WB; IHC; ICC; IP.
PAF878Mu02 Polyclonal Antibody to Secreted Frizzled Related Protein 4 (SFRP4) WB; IHC; ICC; IP.
SEF878Mu ELISA Kit for Secreted Frizzled Related Protein 4 (SFRP4) Enzyme-linked immunosorbent assay for Antigen Detection.
LMF878Mu Multiplex Assay Kit for Secreted Frizzled Related Protein 4 (SFRP4) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.