Gastrokine 1 (GKN1)

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CA11; AMP18; BRICD1; FOV; Foveolin; 18 kDa antrum mucosa protein

Gastrokine 1 (GKN1)
Gastrokine-1 is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.Using differential display of normal and cancerous gastric tissue, followed by 5-prime RACE, Yoshikawa et al. (2000) identified cDNAs encoding CA11 and CAPN9.
The deduced 199-amino acid CA11 protein contains an asn-rich region. Northern blot analysis revealed expression of an approximately 1.1-kb CA11 transcript predominantly in stomach; no expression was detected in cancer tissue or gastric cancer cell lines. Yoshikawa et al. (2000) identified a marker in the CA11 gene that indicates a localization on chromosome 2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC500Hu01 Recombinant Gastrokine 1 (GKN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC500Hu01 Polyclonal Antibody to Gastrokine 1 (GKN1) WB,IHC
MAC500Hu22 Monoclonal Antibody to Gastrokine 1 (GKN1) WB; IHC; ICC; IP.
Assay Kits SEC500Hu ELISA Kit for Gastrokine 1 (GKN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC500Mu01 Recombinant Gastrokine 1 (GKN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC500Mu01 Polyclonal Antibody to Gastrokine 1 (GKN1) WB; IHC; ICC; IP.
Assay Kits SEC500Mu ELISA Kit for Gastrokine 1 (GKN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC500Ra01 Recombinant Gastrokine 1 (GKN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC500Ra01 Polyclonal Antibody to Gastrokine 1 (GKN1) WB; IHC; ICC; IP.
MAC500Ra21 Monoclonal Antibody to Gastrokine 1 (GKN1) WB; IHC; ICC; IP.
Assay Kits SEC500Ra ELISA Kit for Gastrokine 1 (GKN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC500Po01 Recombinant Gastrokine 1 (GKN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC500Po01 Polyclonal Antibody to Gastrokine 1 (GKN1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Gastrokine 1 (GKN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Gastrokine 1 (GKN1) ELISA Kit Customized Service Offer
  1. "Isolation of two novel genes, down-regulated in gastric cancer."Jpn. J. Cancer Res. 91:459-463(2000) [PubMed] [Europe PMC] [Abstract]
  2. "A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa."Am. J. Physiol. 285:G332-G343(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]