Gastrokine-1 is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.Using differential display of normal and cancerous gastric tissue, followed by 5-prime RACE, Yoshikawa et al. (2000) identified cDNAs encoding CA11 and CAPN9.
The deduced 199-amino acid CA11 protein contains an asn-rich region. Northern blot analysis revealed expression of an approximately 1.1-kb CA11 transcript predominantly in stomach; no expression was detected in cancer tissue or gastric cancer cell lines. Yoshikawa et al. (2000) identified a marker in the CA11 gene that indicates a localization on chromosome 2.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC500Hu01 | Recombinant Gastrokine 1 (GKN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC500Hu01 | Polyclonal Antibody to Gastrokine 1 (GKN1) | WB,IHC |
MAC500Hu22 | Monoclonal Antibody to Gastrokine 1 (GKN1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC500Hu | ELISA Kit for Gastrokine 1 (GKN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC500Mu01 | Recombinant Gastrokine 1 (GKN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC500Mu01 | Polyclonal Antibody to Gastrokine 1 (GKN1) | WB; IHC; ICC; IP. |
Assay Kits | SEC500Mu | ELISA Kit for Gastrokine 1 (GKN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC500Ra01 | Recombinant Gastrokine 1 (GKN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC500Ra01 | Polyclonal Antibody to Gastrokine 1 (GKN1) | WB; IHC; ICC; IP. |
MAC500Ra21 | Monoclonal Antibody to Gastrokine 1 (GKN1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC500Ra | ELISA Kit for Gastrokine 1 (GKN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC500Po01 | Recombinant Gastrokine 1 (GKN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC500Po01 | Polyclonal Antibody to Gastrokine 1 (GKN1) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Gastrokine 1 (GKN1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Gastrokine 1 (GKN1) | ELISA Kit Customized Service Offer |
- "Isolation of two novel genes, down-regulated in gastric cancer."Jpn. J. Cancer Res. 91:459-463(2000) [PubMed] [Europe PMC] [Abstract]
- "A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa."Am. J. Physiol. 285:G332-G343(2003) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]